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PA-824

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For Research Use Only | Not For Clinical Use
CATAP187235376
CAS187235-37-6
Structure
Molecular Weight359.26
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to brown
Formpowder
Size10MG, 50MG
Storage Conditions−20°C
1

Drug-Drug Interactions Between PA-824 and Darunavir Based on Pharmacokinetics in Rats by LC-MS-MS

Libin Wang, Jun Zhao, Ruitao Zhang, Le Mi, Xin Shen, Nan Zhou, Tian Feng, Juan Jing, Xueying Liu, Shengyong Zhang

J Chromatogr Sci. 2018 Apr 1;56(4):327-335.

PMID: 29373758

1

PA-824

Tuberculosis (Edinb). 2008 Mar;88(2):134-6.

PMID: 18486052

1

PA-824 , Moxifloxacin and Pyrazinamide Combination Therapy for Tuberculosis

Rodney Dawson, Andreas Diacon

Expert Opin Investig Drugs. 2013 Jul;22(7):927-32.

PMID: 23687915

1

PA-824 Exhibits Time-Dependent Activity in a Murine Model of Tuberculosis

Zahoor Ahmad, Charles A Peloquin, Rajendra P Singh, Hartmut Derendorf, Sandeep Tyagi, Ann Ginsberg, Jacques H Grosset, Eric L Nuermberger

Antimicrob Agents Chemother. 2011 Jan;55(1):239-45.

PMID: 20937781

1

The Nitroimidazooxazines (PA-824 and Analogs): Structure-Activity Relationship and Mechanistic Studies

William A Denny, Brian D Palmer

Future Med Chem. 2010 Aug;2(8):1295-304.

PMID: 21426020

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