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PACMA 31

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For Research Use Only | Not For Clinical Use
CATAP1401089313
CAS1401089-31-3
MDL NumberMFCD26793891
Molecular Weight430.47
InChI KeyAHOOZADJPNUFOQ-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 10 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to light brown
Formpowder
Size5MG, 25MG
Storage Conditionsroom temp
1

Discovery of an Orally Active Small-Molecule Irreversible Inhibitor of Protein Disulfide Isomerase for Ovarian Cancer Treatment

Shili Xu, Alexey N Butkevich, Roppei Yamada, Yu Zhou, Bikash Debnath, Roger Duncan, Ebrahim Zandi, Nicos A Petasis, Nouri Neamati

Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16348-53.

PMID: 22988091

1

Novel Protein Disulfide Isomerase Inhibitor With Anticancer Activity in Multiple Myeloma

Sergei Vatolin, James G Phillips, Babal K Jha, Shravya Govindgari, Jennifer Hu, Dale Grabowski, Yvonne Parker, Daniel J Lindner, Fei Zhong, Clark W Distelhorst, Mitchell R Smith, Claudiu Cotta, Yan Xu, etc.

Cancer Res. 2016 Jun 1;76(11):3340-50.

PMID: 27197150

1

Protein Disulfide Isomerase Inhibition Synergistically Enhances the Efficacy of Sorafenib for Hepatocellular Carcinoma

Jae-Kyung Won, Su Jong Yu, Chae Young Hwang, Sung-Hwan Cho, Sang-Min Park, Kwangsoo Kim, Won-Mook Choi, Hyeki Cho, Eun Ju Cho, Jeong-Hoon Lee, Kyung Bun Lee, Yoon Jun Kim, Kyung-Suk Suh, Ja-June Jang, Chung Yong Kim, etc.

Hepatology. 2017 Sep;66(3):855-868.

PMID: 28439950

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