CAS 23180-57-6 Paeoniflorin - Analytical Products / Alfa Chemistry

CAT	AP23180576-A
CAS	23180-57-6
Structure
MDL Number	MFCD00869331
Synonyms	β-D-Glucopyranoside, 5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl, [1aR-(1aα,2β,3aα,5α,5aα,5bα)]-, Peoniflorin (7CI,8CI), (1aR,2S,3aR,5R,5aR,5bS)-5b-[(Benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl β-D-glucopyranoside,β-D-Glucopyranoside, (1aR,2S,3aR,5R,5aR,5bS)-5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl, NSC 178886, 2,5-Methano-1H-3,4-dioxacyclobuta[cd]pentalene, β-D-glucopyranoside deriv., Paeoniflorin
Molecular Weight	480.46
Molecular Formula	C23H28O11
EC Number	245-476-2
Canonical SMILES	C[C@@]12C[C@@]3(O)O[C@@H](O1)[C@]4(COC(=O)c5ccccc5)[C@H]3C[C@]24O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O
InChI	InChI=1S/C23H28O11/c1-20-9-22(29)13-7-23(20,32-18-16(27)15(26)14(25)12(8-24)31-18)21(13,19(33-20)34-22)10-30-17(28)11-5-3-2-4-6-11/h2-6,12-16,18-19,24-27,29H,7-10H2,1H3/t12-,13-,14-,15+,16-,18+,19-,20+,21+,22-,23+/m1/s1
InChI Key	YKRGDOXKVOZESV-WRJNSLSBSA-N

Description	analytical standard
Accurate Mass	480.1632
API Family	Matrix - API Family See respective official monograph(s)
Assay	≥92.5% (HPLC); ≥90.0% (HPLC)
Form	neat; gas chromatography (GC): suitable
Format	Neat
Grade	analytical standard
Size	10MG
Storage Conditions	2-8°C
Subcategory	British Pharmacopoeia; Product Type: API

1

Effects of Glycyrrhizin on the Pharmacokinetics of Paeoniflorin in Rats and Its Potential Mechanism

Hongjuan Sun, Jingfeng Wang, Juan Lv

Pharm Biol. 2019 Dec;57(1):550-554.

PMID: 31429612

1

Gut Microbiota-Based Pharmacokinetics and the Antidepressant Mechanism of Paeoniflorin

Jin-Bo Yu, Zhen-Xiong Zhao, Ran Peng, Li-Bin Pan, Jie Fu, Shu-Rong Ma, Pei Han, Lin Cong, Zheng-Wei Zhang, Li-Xin Sun, Jian-Dong Jiang, Yan Wang

Front Pharmacol. 2019 Mar 20;10:268.

PMID: 30949054

1

Neuroprotective Effect of Paeoniflorin on Okadaic Acid-Induced Tau Hyperphosphorylation via calpain/Akt/GSK-3β Pathway in SH-SY5Y Cells

Xiao-Hui Ma, Wen-Jun Duan, You-Sheng Mo, Jun-Li Chen, Shi Li, Wei Zhao, Lei Yang, Sui-Qing Mi, Xin-Liang Mao, Hong Wang, Qi Wang

Brain Res. 2018 Jul 1;1690:1-11.

PMID: 29596798

1

The Regulatory Effects of Paeoniflorin and Its Derivative Paeoniflorin-6'-O-Benzene Sulfonate CP-25 on Inflammation and Immune Diseases

Jiajie Tu, Yawei Guo, Wenming Hong, Yilong Fang, Dafei Han, Pengying Zhang, Xinming Wang, Heinrich Körner, Wei Wei

Front Pharmacol. 2019 Feb 5;10:57.

PMID: 30804784

1

WITHDRAWN: Paeoniflorin Attenuates LPS-induced Inflammation in Nucleus Pulposus Cells via Nrf-2/HO-1/HMGB1/NF-κB Pathway

Yin Heng, Wu Mao, Ma Yong, Guo Yang, Qiuju Su, Jianwei Wang

Microb Pathog. 2018 Aug 8;S0882-4010(18)30088-3.

PMID: 30096430