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Palbociclib

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For Research Use Only | Not For Clinical Use
CATAP571190302
CAS571190-30-2
Structure
Molecular Weight447.53
Description≥98% (HPLC)
Solubility0.1 M HCl: 2 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditionsroom temp
1

Fulvestrant Plus Palbociclib Versus Fulvestrant Plus Placebo for Treatment of Hormone-Receptor-Positive, HER2-negative Metastatic Breast Cancer That Progressed on Previous Endocrine Therapy (PALOMA-3): Final Analysis of the Multicentre, Double-Blind, Phase 3 Randomised Controlled Trial

Massimo Cristofanilli, Nicholas C Turner, Igor Bondarenko, Jungsil Ro, Seock-Ah Im, Norikazu Masuda, Marco Colleoni, Angela DeMichele, Sherene Loi, Sunil Verma, Hiroji Iwata, Nadia Harbeck, Ke Zhang, Kathy Puyana Theall, etc.

Lancet Oncol. 2016 Apr;17(4):425-439.

PMID: 26947331

1

Overall Survival With Palbociclib and Fulvestrant in Advanced Breast Cancer

Nicholas C Turner, Dennis J Slamon, Jungsil Ro, Igor Bondarenko, Seock-Ah Im, Norikazu Masuda, Marco Colleoni, Angela DeMichele, Sherene Loi, Sunil Verma, Hiroji Iwata, Nadia Harbeck, Sibylle Loibl, Fabrice André, etc.

N Engl J Med. 2018 Nov 15;379(20):1926-1936.

PMID: 30345905

1

Palbociclib and Letrozole in Advanced Breast Cancer

Richard S Finn, Miguel Martin, Hope S Rugo, Stephen Jones, Seock-Ah Im, Karen Gelmon, Nadia Harbeck, Oleg N Lipatov, Janice M Walshe, Stacy Moulder, Eric Gauthier, Dongrui R Lu, Sophia Randolph, Véronique Diéras, etc.

N Engl J Med. 2016 Nov 17;375(20):1925-1936.

PMID: 27959613

1

Palbociclib in Hormone-Receptor-Positive Advanced Breast Cancer

Nicholas C Turner, Jungsil Ro, Fabrice André, Sherene Loi, Sunil Verma, Hiroji Iwata, Nadia Harbeck, Sibylle Loibl, Cynthia Huang Bartlett, Ke Zhang, Carla Giorgetti, Sophia Randolph, Maria Koehler, Massimo Cristofanilli, etc.

N Engl J Med. 2015 Jul 16;373(3):209-19.

PMID: 26030518

1

Palbociclib Plus Letrozole as First-Line Therapy in Estrogen receptor-positive/human Epidermal Growth Factor Receptor 2-negative Advanced Breast Cancer With Extended Follow-Up

H S Rugo, R S Finn, V Diéras, J Ettl, O Lipatov, A A Joy, N Harbeck, A Castrellon, S Iyer, D R Lu, A Mori, E R Gauthier, C Huang Bartlett, K A Gelmon, D J Slamon

Breast Cancer Res Treat. 2019 Apr;174(3):719-729.

PMID: 30632023

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