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PARP5A active human

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For Research Use Only | Not For Clinical Use
CATIAR4246444
Descriptionrecombinant, expressed in baculovirus infected Sf9 cells, ≥30% (SDS-PAGE)
Assay≥30% (SDS-PAGE)
Formaqueous solution
Size10μG
Storage Conditions−70°C
1

Complex Roles of Members of the ADP-ribosyl Transferase Super Family in Immune Defences: Looking Beyond PARP1

Iain Welsby, David Hutin, Oberdan Leo

Biochem Pharmacol. 2012 Jul 1;84(1):11-20.

PMID: 22402301

1

E7449: A Dual Inhibitor of PARP1/2 and tankyrase1/2 Inhibits Growth of DNA Repair Deficient Tumors and Antagonizes Wnt Signaling

Sharon McGonigle, Zhihong Chen, Jiayi Wu, Paul Chang, Donna Kolber-Simonds, Karen Ackermann, Natalie C Twine, Jue-Lon Shie, Jingzang Tao Miu, Kuan-Chun Huang, George A Moniz, Kenichi Nomoto

Oncotarget. 2015 Dec 1;6(38):41307-23.

PMID: 26513298

1

Insights Into the Binding of PARP Inhibitors to the Catalytic Domain of Human tankyrase-2

Wei Qiu, Robert Lam, Oleksandr Voytyuk, Vladimir Romanov, Roni Gordon, Simon Gebremeskel, Jakub Vodsedalek, Christine Thompson, Irina Beletskaya, Kevin P Battaile, Emil F Pai, Robert Rottapel, Nickolay Y Chirgadze

Acta Crystallogr D Biol Crystallogr. 2014 Oct;70(Pt 10):2740-53.

PMID: 25286857

1

PARPs and PAR as Novel Pharmacological Targets for the Treatment of Stress Granule-Associated Disorders

Giovanna Grimaldi, Giuliana Catara, Luca Palazzo, Annunziata Corteggio, Carmen Valente, Daniela Corda

Biochem Pharmacol. 2019 Sep;167:64-75.

PMID: 31102582

1

Structural Basis for tankyrase-RNF146 Interaction Reveals Noncanonical Tankyrase-Binding Motifs

Paul A DaRosa, Rachel E Klevit, Wenqing Xu

Protein Sci. 2018 Jun;27(6):1057-1067.

PMID: 29604130

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