CAS 354759-10-7 PBOX-15 - Analytical Products / Alfa Chemistry

CAT	AP354759107
CAS	354759-10-7
Molecular Weight	417.46

Description	≥98% (HPLC)
Solubility	DMSO: 15 mg/mL, clear
Assay	≥98% (HPLC)
Color	white to beige
Form	powder
Size	5MG, 25MG
Storage Conditions	2-8°C

1

A New Microtubule-Targeting Compound PBOX-15 Inhibits T-cell Migration via Post-Translational Modifications of Tubulin

Navin K Verma, Eugene Dempsey, Jennifer Conroy, Peter Olwell, Anthony M Mcelligott, Anthony M Davies, Dermot Kelleher, Stefania Butini, Giuseppe Campiani, D Clive Williams, Daniela M Zisterer, Mark Lawler, etc.

J Mol Med (Berl). 2008 Apr;86(4):457-69.

PMID: 18270678

1

Microtubule-targeting-compound PBOX-15 Radiosensitizes Cancer Cells in Vitro

James C Forde, Elaina N Maginn, Gillian McNamara, Lynn M Martin, Guiseppe Campiani, D Clive Williams, Daniela Zisterer, Anthony M McElligott, Mark Lawler, Thomas H Lynch, Donal Hollywood, Laure Marignol

Cancer Biol Ther. 2011 Feb 15;11(4):421-8.

PMID: 21131779

1

PBOX-15 Induces Apoptosis and Improves the Efficacy of Oxaliplatin in Human Colorectal Cancer Cell Lines

Giuseppina Gangemi, Patrizia Gazzerro, Donatella Fiore, Maria Chiara Proto, Stefania Butini, Sandra Gemma, Alice Casagni, Chiara Laezza, Mario Vitale, Alessia Ligresti, Vincenzo Di Marzo, Daniela M Zisterer, etc.

Eur J Pharmacol. 2013 Aug 15;714(1-3):379-87.

PMID: 23872382

1

PBOX-15, a Novel Microtubule Targeting Agent, Induces Apoptosis, Upregulates Death Receptors, and Potentiates TRAIL-mediated Apoptosis in Multiple Myeloma Cells

E N Maginn, P V Browne, P Hayden, E Vandenberghe, B MacDonagh, P Evans, M Goodyer, P Tewari, G Campiani, S Butini, D C Williams, D M Zisterer, M P Lawler, A M McElligott

Br J Cancer. 2011 Jan 18;104(2):281-9.

PMID: 21179037

1

The Microtubule Targeting Agent PBOX-15 Inhibits Integrin-Mediated Cell Adhesion and Induces Apoptosis in Acute Lymphoblastic Leukaemia Cells

Joanne Lysaght, Navin K Verma, Elaina N Maginn, Jacqueline M Ryan, Giuseppe Campiani, Daniela M Zisterer, D Clive Williams, Paul V Browne, Mark P Lawler, Anthony M McElligott

Int J Oncol. 2013 Jan;42(1):239-46.

PMID: 23135704

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