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PD-161989 2-Hydroxyethanesulfonate

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For Research Use Only | Not For Clinical Use
CATALP186268075
CAS186268-07-5 (free base)
MDL NumberMFCD18452848
Molecular Weight430.43
InChI KeyKFHUCRVOUVNJSQ-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityH2O: ≥10 mg/mL
Assay≥98% (HPLC)
Colorwhite to off-white
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

A Glycyl Radical Enzyme Enables Hydrogen Sulfide Production by the Human Intestinal Bacterium

Spencer C Peck, Karin Denger, Anna Burrichter, Stephania M Irwin, Emily P Balskus, David Schleheck

Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3171-3176.

PMID: 30718429

1

Antitumor Activity of Ethyl 5-amino-1,2-dihydro-2-methyl-3-phenyl-pyrido [3,4-b]pyrazin-7-ylcarbamate, 2-hydroxyethanesulfonate, Hydrate (NSC 370147) Against Selected Tumor Systems in Culture and in Mice

W R Waud, W R Leopold, W L Elliott, D J Dykes, W R Laster Jr, C G Temple Jr, S D Harrison Jr, D P Griswold Jr

Cancer Res. 1990 Jun 1;50(11):3239-44.

PMID: 2334919

1

Antitumor Drug Cross-Resistance in Vivo in a Murine P388 Leukemia Resistant to Ethyl 5-amino-1,2-dihydro-2-methyl-3-phenylpyrido[3,4-b]pyrazin-7 - Ylcarbamate 2-hydroxyethanesulfonate Hydrate (NSC 370,147) 370147

W R Waud, S D Harrison Jr, C G Temple Jr, D P Griswold Jr

Cancer Chemother Pharmacol. 1992;29(3):190-4.

PMID: 1733551

1

Plasma Metabolites Associated With Type 2 Diabetes in a Swedish Population: A Case-Control Study Nested in a Prospective Cohort

Lin Shi, Carl Brunius, Marko Lehtonen, Seppo Auriola, Ingvar A Bergdahl, Olov Rolandsson, Kati Hanhineva, Rikard Landberg

Diabetologia. 2018 Apr;61(4):849-861.

PMID: 29349498

1

Sulfidogenesis From 2-aminoethanesulfonate (Taurine) Fermentation by a Morphologically Unusual Sulfate-Reducing Bacterium, Desulforhopalus Singaporensis Sp. Nov

T J Lie, M L Clawson, W Godchaux, E R Leadbetter

Appl Environ Microbiol. 1999 Aug;65(8):3328-34.

PMID: 10427015

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