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PD 169316

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For Research Use Only | Not For Clinical Use
CATAP152121534-A
CAS152121-53-4
MDL NumberMFCD12405019
Molecular Weight360.34
InChI KeyBGIYKDUASORTBB-UHFFFAOYSA-N
Description≥98% (HPLC), solid
SolubilityDMSO: >10 mg/mL; H2O: insoluble
Assay≥98% (HPLC)
Colorfaint yellow to dark orange
Formsolid
Size5MG, 25MG
Storage Conditions2-8°C
1

A Novel Platinum Complex Containing a Piplartine Derivative Exhibits Enhanced Cytotoxicity, Causes Oxidative Stress and Triggers Apoptotic Cell Death by ERK/p38 Pathway in Human Acute Promyelocytic Leukemia HL-60 Cells

Maiara de S Oliveira, Marília I F Barbosa, Thiago Belarmino de Souza, Diogo R M Moreira, Felipe Terra Martins, Wilmer Villarreal, Rafael P Machado, Antônio Carlos Doriguetto, Milena B P Soares, Daniel P Bezerra

Redox Biol. 2019 Jan;20:182-194.

PMID: 30359932

1

High-intensity p38 Kinase Activity Is Critical for p21(cip1) Induction and the Antiproliferative Function of G(i) Protein-Coupled Receptors

F Alderton, P P Humphrey, L A Sellers

Mol Pharmacol. 2001 May;59(5):1119-28.

PMID: 11306695

1

p38 Mitogen-activated Protein Kinase Modulates Exocrine Secretion in Rabbit Lacrimal Gland

Stina K Carlsson, J Peter Gierow

Cell Mol Biol Lett. 2012 Mar;17(1):1-10.

PMID: 22069054

1

Protein Kinase Inhibitors Can Suppress Stress-Induced Dissociation of Hsp27

K Kato, H Ito, I Iwamoto, K Lida, Y Inaguma

Cell Stress Chaperones. 2001 Jan;6(1):16-20.

PMID: 11525238

1

The p38 MAP Kinase Inhibitor, PD 169316, Inhibits Flagellar Motility in Leishmania Donovani

G Srinivas Reddy, Aakash Gautam Mukhopadhyay, Chinmoy Sankar Dey

Biochem Biophys Res Commun. 2017 Dec 2;493(4):1425-1429.

PMID: 28958943

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