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PD 173074

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For Research Use Only | Not For Clinical Use
CATAP219580117-B
CAS219580-11-7
Structure
MDL NumberMFCD08705327
Molecular Weight523.67
InChI KeyDXCUKNQANPLTEJ-UHFFFAOYSA-N
Description≥96% (HPLC), powder
SolubilityDMSO: 10 mg/mL, clear
Assay≥96% (HPLC)
Colorfaintly yellow to dark yellow
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Crystal Structure of an Angiogenesis Inhibitor Bound to the FGF Receptor Tyrosine Kinase Domain

M Mohammadi, S Froum, J M Hamby, M C Schroeder, R L Panek, G H Lu, A V Eliseenkova, D Green, J Schlessinger, S R Hubbard

EMBO J. 1998 Oct 15;17(20):5896-904.

PMID: 9774334

1

Deregulation of FGFR1 and CDK6 Oncogenic Pathways in Acute Lymphoblastic Leukaemia Harbouring Epigenetic Modifications of the MIR9 Family

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Br J Haematol. 2011 Oct;155(1):73-83.

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1

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PMID: 18940940

1

The FGFR1 Inhibitor PD 173074 Selectively and Potently Antagonizes FGF-2 Neurotrophic and Neurotropic Effects

S D Skaper, W J Kee, L Facci, G Macdonald, P Doherty, F S Walsh

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PMID: 10987832

1

The Role of HGF/MET and FGF/FGFR in Fibroblast-Derived Growth Stimulation and Lapatinib-Resistance of Esophageal Squamous Cell Carcinoma

Shin Saito, Kazue Morishima, Takashi Ui, Hiroko Hoshino, Daisuke Matsubara, Shumpei Ishikawa, Hiroyuki Aburatani, Masashi Fukayama, Yoshinori Hosoya, Naohiro Sata, Alan K Lefor, Yoshikazu Yasuda, Toshiro Niki

BMC Cancer. 2015 Feb 25;15:82.

PMID: 25884729

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