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PD-184161

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For Research Use Only | Not For Clinical Use
CATAP212631679
CAS212631-67-9
MDL NumberMFCD16038897
Molecular Weight557.56
InChI KeyVJNZMSLGVUSPCF-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: >10 mg/mL
Assay≥98% (HPLC)
Colorwhite to off-white
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Effects of Ketamine Administration on the Phosphorylation Levels of CREB and TrKB and on Oxidative Damage After Infusion of MEK Inhibitor

Gislaine Z Réus, Helena M Abaleira, Stephanie E Titus, Camila O Arent, Monique Michels, Jaine R da Luz, Maria Augusta B dos Santos, Anelise S Carlessi, Beatriz I Matias, Livia Bruchchen, Amanda V Steckert, etc.

Pharmacol Rep. 2016 Feb;68(1):177-84.

PMID: 26721370

1

ERK Inhibition With PD184161 Mitigates Brain Damage in a Mouse Model of Stroke

Amadeus Gladbach, Janet van Eersel, Mian Bi, Yazi D Ke, Lars M Ittner

J Neural Transm (Vienna). 2014 May;121(5):543-7.

PMID: 24337667

1

MAPK Signaling Correlates With the Antidepressant Effects of Ketamine

Gislaine Z Réus, Flavio Geraldo Vieira, Helena M Abelaira, Monique Michels, Débora B Tomaz, Maria Augusta B dos Santos, Anelise S Carlessi, Morgana V Neotti, Beatriz I Matias, Jaíne R Luz, Felipe Dal-Pizzol, etc.

J Psychiatr Res. 2014 Aug;55:15-21.

PMID: 24819632

1

Role of Runx2 in IGF-1Rβ/Akt- And AMPK/Erk-dependent Growth, Survival and Sensitivity Towards Metformin in Breast Cancer Bone Metastasis

M Tandon, Z Chen, A H Othman, J Pratap

Oncogene. 2016 Sep 8;35(36):4730-40.

PMID: 26804175

1

Selective HIF-1 Regulation Under Nonhypoxic Conditions by the p42/p44 MAP Kinase Inhibitor PD184161

Maroua Jalouli, Sophie Mokas, Catherine A Turgeon, Laurent Lamalice, Darren E Richard

Mol Pharmacol. 2017 Nov;92(5):510-518.

PMID: 28814529

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