PD-L1/CD274/B7-H1 human - Analytical Products / Alfa Chemistry

CAT

IAR42413193

Description	recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
Assay	≥95% (SDS-PAGE)
Form	lyophilized; observed mol wt 35-42 kDa (DTT-reduced. Protein migrates due to glycosylation. Phe 19 is the predicted N-terminal.)
Size	10UG, 50UG
Storage Conditions	−20°C

1

Antagonist Antibodies to PD-1 and B7-H1 (PD-L1) in the Treatment of Advanced Human Cancer

Mario Sznol, Lieping Chen

Clin Cancer Res. 2013 Mar 1;19(5):1021-34.

PMID: 23460533

1

MPDL3280A (anti-PD-L1) Treatment Leads to Clinical Activity in Metastatic Bladder Cancer

Thomas Powles, Joseph Paul Eder, Gregg D Fine, Fadi S Braiteh, Yohann Loriot, Cristina Cruz, Joaquim Bellmunt, Howard A Burris, Daniel P Petrylak, Siew-leng Teng, Xiaodong Shen, Zachary Boyd, Priti S Hegde, etc.

Nature. 2014 Nov 27;515(7528):558-62.

PMID: 25428503

1

Predictive Correlates of Response to the anti-PD-L1 Antibody MPDL3280A in Cancer Patients

Roy S Herbst, Jean-Charles Soria, Marcin Kowanetz, Gregg D Fine, Omid Hamid, Michael S Gordon, Jeffery A Sosman, David F McDermott, John D Powderly, Scott N Gettinger, Holbrook E K Kohrt, Leora Horn, Donald P Lawrence, etc.

Nature. 2014 Nov 27;515(7528):563-7.

PMID: 25428504

1

Targeting B7-H1 (PD-L1) Sensitizes Cancer Cells to Chemotherapy

Xiaosheng Wu, Yanli Li, Xin Liu, Chunhua Chen, Susan M Harrington, Siyu Cao, Tiancheng Xie, Tu Pham, Aaron S Mansfield, Yiyi Yan, Eugene D Kwon, Liewei Wang, Kun Ling, Haidong Dong

Heliyon. 2018 Dec 18;4(12):e01039.

PMID: 30603685

1

Tumor Cell-Intrinsic CD274/PD-L1: A Novel Metabolic Balancing Act With Clinical Potential

Curtis A Clark, Harshita B Gupta, Tyler J Curiel

Autophagy. 2017 May 4;13(5):987-988.

PMID: 28368722

* Products or Services Interested: PD-L1/CD274/B7-H1 human ()
* Your question
* Name
* Email
Verification Code