0

PD166326

INQUIRY Add to cart
For Research Use Only | Not For Clinical Use
CATAP185039912
CAS185039-91-2
Molecular Weight427.28
Description≥98% (HPLC)
SolubilityDMSO: 2 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to light brown
Formpowder
Size5MG, 25MG
Storage Conditionsroom temp
1

A Cell-Based Screen for Resistance of Bcr-Abl-positive Leukemia Identifies the Mutation Pattern for PD166326, an Alternative Abl Kinase Inhibitor

Nikolas von Bubnoff, Darren R Veach, Heiko van der Kuip, Walter E Aulitzky, Jana Sänger, Petra Seipel, William G Bornmann, Christian Peschel, Bayard Clarkson, Justus Duyster

Blood. 2005 Feb 15;105(4):1652-9.

PMID: 15459011

1

A Novel Pyridopyrimidine Inhibitor of Abl Kinase Is a Picomolar Inhibitor of Bcr-abl-driven K562 Cells and Is Effective Against STI571-resistant Bcr-abl Mutants

David R Huron, Mercedes E Gorre, Alan J Kraker, Charles L Sawyers, Neal Rosen, Mark M Moasser

Clin Cancer Res. 2003 Apr;9(4):1267-73.

PMID: 12684394

1

Gene Expression Profiling of Imatinib and PD166326-resistant CML Cell Lines Identifies Fyn as a Gene Associated With Resistance to BCR-ABL Inhibitors

Sébastien Grosso, Alexandre Puissant, Maeva Dufies, Pascal Colosetti, Arnaud Jacquel, Kevin Lebrigand, Pascal Barbry, Marcel Deckert, Jill Patrice Cassuto, Bernard Mari, Patrick Auberger

Mol Cancer Ther. 2009 Jul;8(7):1924-33.

PMID: 19567819

1

PD166326, a Novel Tyrosine Kinase Inhibitor, Has Greater Antileukemic Activity Than Imatinib Mesylate in a Murine Model of Chronic Myeloid Leukemia

Nicholas C Wolff, Darren R Veach, William P Tong, William G Bornmann, Bayard Clarkson, Robert L Ilaria Jr

Blood. 2005 May 15;105(10):3995-4003.

PMID: 15657179

1

The Bcr-Abl Tyrosine Kinase Inhibitor Imatinib and Promising New Agents Against Philadelphia Chromosome-Positive Leukemias

Taira Maekawa, Eishi Ashihara, Shinya Kimura

Int J Clin Oncol. 2007 Oct;12(5):327-40.

PMID: 17929114

  • Verification code
Contact Us

Send Us a Request

What is your specific need? We will do everything we can to meet your expectations.
Online Inquiry

Online Inquiry

For any inquiry, question or recommendation, please call: or fill out the following form.

  • Verification code

Head Office

  • Tel:
  • Email:

Follow us on

qrcode