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PDE2A active rat

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For Research Use Only | Not For Clinical Use
CATIAR4245716
Descriptionrecombinant, expressed in baculovirus infected Sf9 cells, ≥56% (SDS-PAGE)
Assay≥56% (SDS-PAGE)
Formaqueous solution
Size5μG
Storage Conditions−70°C
1

Design and Synthesis of Novel and Selective Phosphodiesterase 2 (PDE2a) Inhibitors for the Treatment of Memory Disorders

Laurent Gomez, Mark Eben Massari, Troy Vickers, Graeme Freestone, William Vernier, Kiev Ly, Rui Xu, Margaret McCarrick, Tami Marrone, Markus Metz, Yingzhou G Yan, Zachary W Yoder, Robert Lemus, Nicola J Broadbent, etc.

J Med Chem. 2017 Mar 9;60(5):2037-2051.

PMID: 28165743

1

Inhibition of PDE2A, but Not PDE9A, Modulates Presynaptic Short-Term Plasticity Measured by Paired-Pulse Facilitation in the CA1 Region of the Hippocampus

Diego Fernández-Fernández, Holger Rosenbrock, Katja S Kroker

Synapse. 2015 Oct;69(10):484-96.

PMID: 26178667

1

Pharmacological Characterization of a Novel Potent, Selective, and Orally Active Phosphodiesterase 2A Inhibitor, PDM-631

Shunsuke Maehara, Keita Arakawa, Kotaro Hoshida, Hiroshi Nagasue, Noboru Chida, Kazunari Nakao, Shoji Furusako

Eur J Pharmacol. 2017 Sep 15;811:110-116.

PMID: 28587776

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