PDE4D7 active human - Analytical Products / Alfa Chemistry

CAT

IAR4245719

Description	recombinant, expressed in baculovirus infected Sf9 cells, ≥65% (SDS-PAGE)
Assay	≥65% (SDS-PAGE)
Form	aqueous solution
Size	5μG
Storage Conditions	−70°C

1

Cloning and Characterization of Novel PDE4D Isoforms PDE4D6 and PDE4D7

Daguang Wang, Chengjun Deng, Bozena Bugaj-Gaweda, May Kwan, Caryn Gunwaldsen, Chris Leonard, Xiaonan Xin, Yinghe Hu, Axel Unterbeck, Michael De Vivo

Cell Signal. 2003 Sep;15(9):883-91.

PMID: 12834813

1

Creating a Potential Diagnostic for Prostate Cancer Risk Stratification (InformMDx™) by Translating Novel Scientific Discoveries Concerning cAMP Degrading phosphodiesterase-4D7 (PDE4D7)

Dave J P Henderson, Miles D Houslay, Chris H Bangma, Ralf Hoffmann

Clin Sci (Lond). 2019 Jan 25;133(2):269-286.

PMID: 30683712

1

Discovery of Arylbenzylamines as PDE4 Inhibitors With Potential Neuroprotective Effect

Lv Tang, Chang Huang, Jiahong Zhong, JiaPeng He, Jiayin Guo, Menghua Liu, Jiang-Ping Xu, Hai-Tao Wang, Zhong-Zhen Zhou

Eur J Med Chem. 2019 Apr 15;168:221-231.

PMID: 30822711

1

The Activity of cAMP-phosphodiesterase 4D7 (PDE4D7) Is Regulated by Protein Kinase A-dependent Phosphorylation Within Its Unique N-terminus

Ashleigh M Byrne, Christina Elliott, Ralf Hoffmann, George S Baillie

FEBS Lett. 2015 Mar 12;589(6):750-5.

PMID: 25680530

1

The cAMP phosphodiesterase-4D7 (PDE4D7) Is Downregulated in Androgen-Independent Prostate Cancer Cells and Mediates Proliferation by Compartmentalising cAMP at the Plasma Membrane of VCaP Prostate Cancer Cells

D J P Henderson, A Byrne, K Dulla, G Jenster, R Hoffmann, G S Baillie, M D Houslay

Br J Cancer. 2014 Mar 4;110(5):1278-87.

PMID: 24518597

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