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Pelitinib

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For Research Use Only | Not For Clinical Use
CATAP257933827
CAS257933-82-7
Structure
Molecular Weight467.92
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder; protect from light
Size5MG, 25MG
Storage Conditions−20°C
1

[Employing Tyrosine Kinase Inhibitors in the First Line Treatment of EGFR-positive Metastatic NSCLC - State of the Art and Recent Developments]

R Wiewrodt, M Serke, C Grohé, W Brückl

Pneumologie. 2013 Sep;67(9):494-501.

PMID: 24006195

1

Inhibition of Epidermal Growth Factor Receptor Improves Antitumor Efficacy of Vemurafenib in BRAF-mutant Human Melanoma in Preclinical Model

István Kenessey, Zsófia Kramer, Lilla István, Mihály T Cserepes, Tamás Garay, Balázs Hegedűs, Judit Dobos, József Tímár, József Tóvári

Melanoma Res. 2018 Dec;28(6):536-546.

PMID: 30124539

1

Pelitinib (EKB-569) Targets the Up-Regulation of ABCB1 and ABCG2 Induced by Hyperthermia to Eradicate Lung Cancer

Kenneth K W To, Daniel C Poon, Yuming Wei, Fang Wang, Ge Lin, Liwu Fu

Br J Pharmacol. 2015 Aug;172(16):4089-106.

PMID: 25988710

1

Small Molecule Inhibitors Targeting the EGFR/ErbB Family of Protein-Tyrosine Kinases in Human Cancers

Robert Roskoski Jr

Pharmacol Res. 2019 Jan;139:395-411.

PMID: 30500458

1

The PI3 kinase/mTOR Blocker NVP-BEZ235 Overrides Resistance Against Irreversible ErbB Inhibitors in Breast Cancer Cells

Caroline Brünner-Kubath, Waheed Shabbir, Victoria Saferding, Renate Wagner, Christian F Singer, Peter Valent, Walter Berger, Brigitte Marian, Christoph C Zielinski, Michael Grusch, Thomas W Grunt

Breast Cancer Res Treat. 2011 Sep;129(2):387-400.

PMID: 21046231

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