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PF-02413873

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For Research Use Only | Not For Clinical Use
CATAP936345356
CAS936345-35-6
MDL NumberMFCD16987601
Molecular Weight359.44
Description≥98% (HPLC)
SolubilityDMSO: 2 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditionsroom temp
1

Preclinical and Clinical Pharmacokinetics of PF-02413873, a Nonsteroidal Progesterone Receptor Antagonist

Peter J Bungay, Sarah Tweedy, David C Howe, Karl R Gibson, Hannah M Jones, Natalie M Mount

Drug Metab Dispos. 2011 Aug;39(8):1396-405.

PMID: 21543556

1

Progesterone Antagonizes Dexamethasone-Regulated Surfactant Proteins In Vitro

Steffen Kunzmann, Barbara Ottensmeier, Christian P Speer, Markus Fehrholz

Reprod Sci. 2019 Aug;26(8):1062-1070.

PMID: 30317939

1

The Translational Efficacy of a Nonsteroidal Progesterone Receptor Antagonist, 4-[3-cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy,-2,6-dimethylbenzonitrile (PF-02413873), on Endometrial Growth in Macaque and Human

David C Howe, Natalie M Mount, Kirsty Bess, Amy Brown, Peter Bungay, Karl R Gibson, Tony Hawcock, Jacques Richard, Gareth Jones, Rosalind Walley, Alison McLeod, Coralie Apfeldorfer, Simeon Ramsey, Sarah Tweedy, etc.

J Pharmacol Exp Ther. 2011 Nov;339(2):642-53.

PMID: 21849626

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