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PF-04418948

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For Research Use Only | Not For Clinical Use
CATAP1078166570
CAS1078166-57-0
Molecular Weight409.41
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditionsroom temp
1

Glial interleukin-1β Upregulates Neuronal Sodium Channel 1.7 in Trigeminal Ganglion Contributing to Temporomandibular Joint Inflammatory Hypernociception in Rats

Peng Zhang, Rui-Yun Bi, Ye-Hua Gan

J Neuroinflammation. 2018 Apr 20;15(1):117.

PMID: 29678208

1

In Vitro and in Vivo Characterization of PF-04418948, a Novel, Potent and Selective Prostaglandin EP₂ Receptor Antagonist

K J af Forselles, J Root, T Clarke, D Davey, K Aughton, K Dack, N Pullen

Br J Pharmacol. 2011 Dec;164(7):1847-56.

PMID: 21595651

1

Prostaglandin E

Tomohiro Aoki, Shuh Narumiya

Inflamm Regen. 2017 Mar 1;37:4.

PMID: 29259703

1

Prostanoid EP₂ Receptors Are Up-Regulated in Human Pulmonary Arterial Hypertension: A Key Anti-Proliferative Target for Treprostinil in Smooth Muscle Cells

Jigisha A Patel, Lei Shen, Susan M Hall, Chabha Benyahia, Xavier Norel, Robin J McAnulty, Shahin Moledina, Adam M Silverstein, Brendan J Whittle, Lucie H Clapp

Int J Mol Sci. 2018 Aug 12;19(8):2372.

PMID: 30103548

1

Selectivity Profiling of the Novel EP2 Receptor Antagonist, PF-04418948, in Functional Bioassay Systems: Atypical Affinity at the Guinea Pig EP2 Receptor

Mark A Birrell, Sarah A Maher, James Buckley, Nicole Dale, Sara Bonvini, Kristof Raemdonck, Nick Pullen, Mark A Giembycz, Maria G Belvisi

Br J Pharmacol. 2013 Jan;168(1):129-38.

PMID: 22747912

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