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PF-04449913 maleate salt

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For Research Use Only | Not For Clinical Use
CATALP1095173275
CAS1095173-27-5 (free base)
MDL NumberMFCD29037212
Molecular Weight490.51
InChI KeyVJCVKWFBWAVYOC-UIXXXISESA-N
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditionsroom temp
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Evaluation of the Effect of New Formulation, Food, or a Proton Pump Inhibitor on the Relative Bioavailability of the Smoothened Inhibitor Glasdegib (PF-04449913) in Healthy Volunteers

Nagdeep Giri, Lisa H Lam, Robert R LaBadie, Joseph F Krzyzaniak, Hong Jiang, Brian Hee, Yali Liang, M Naveed Shaik

Cancer Chemother Pharmacol. 2017 Dec;80(6):1249-1260.

PMID: 29086063

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Evaluation of the Effects of Formulation, Food, or a Proton-Pump Inhibitor on the Pharmacokinetics of Glasdegib (PF-04449913) in Healthy Volunteers: A Randomized Phase I Study

Naveed Shaik, Brian Hee, Hua Wei, Robert R LaBadie

Cancer Chemother Pharmacol. 2019 Mar;83(3):463-472.

PMID: 30536154

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