CAS 1430806-04-4 PF-05089771 - Analytical Products / Alfa Chemistry

CAT	AP1430806044
CAS	1430806-04-4
Molecular Weight	672.56
InChI Key	NVKBPDYKPNYMDR-UHFFFAOYSA-N

Description	≥98% (HPLC)
Solubility	DMSO: 30 mg/mL, clear
Assay	≥98% (HPLC)
Color	white to beige
Form	powder
Size	5MG, 25MG
Storage Conditions	room temp

1

Clinical Micro-Dose Studies to Explore the Human Pharmacokinetics of Four Selective Inhibitors of Human Nav1.7 Voltage-Dependent Sodium Channels

Hannah M Jones, Richard P Butt, Rob W Webster, Ian Gurrell, Pawel Dzygiel, Neil Flanagan, Daniela Fraier, Tanya Hay, Laura Else Iavarone, Jacquelynn Luckwell, Hannah Pearce, Alex Phipps, Jill Segelbacher, etc.

Clin Pharmacokinet. 2016 Jul;55(7):875-887.

PMID: 26895021

1

Efficacy of the Nav1.7 Blocker PF-05089771 in a Randomised, Placebo-Controlled, Double-Blind Clinical Study in Subjects With Painful Diabetic Peripheral Neuropathy

Aoibhinn McDonnell, Susie Collins, Zahid Ali, Laura Iavarone, Raulin Surujbally, Simon Kirby, Richard P Butt

Pain. 2018 Aug;159(8):1465-1476.

PMID: 29578944

1

Mechanism-specific Assay Design Facilitates the Discovery of Nav1.7-selective Inhibitors

Tania Chernov-Rogan, Tianbo Li, Gang Lu, Henry Verschoof, Kuldip Khakh, Steven W Jones, Maureen H Beresini, Chang Liu, Daniel F Ortwine, Steven J McKerrall, David H Hackos, Daniel Sutherlin, Charles J Cohen, etc.

Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E792-E801.

PMID: 29311306

1

Primary Erythromelalgia: A Review

Zhaoli Tang, Zhao Chen, Beisha Tang, Hong Jiang

Orphanet J Rare Dis. 2015 Sep 30;10:127.

PMID: 26419464

1

The Selective Nav1.7 Inhibitor, PF-05089771, Interacts Equivalently With Fast and Slow Inactivated Nav1.7 Channels

Jonathan W Theile, Matthew D Fuller, Mark L Chapman

Mol Pharmacol. 2016 Nov;90(5):540-548.

PMID: 27587537

* Products or Services Interested: PF-05089771 (1430806-04-4)
* Your question
* Name
* Email
Verification Code