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PF-06928215

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For Research Use Only | Not For Clinical Use
CATIAR4244767
Molecular Weight380.40
Description≥98% (HPLC)
SolubilityDMSO: 2 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditionsroom temp
1

Discovery of PF-06928215 as a High Affinity Inhibitor of cGAS Enabled by a Novel Fluorescence Polarization Assay

Justin Hall, Amy Brault, Fabien Vincent, Shawn Weng, Hong Wang, Darren Dumlao, Ann Aulabaugh, Dikran Aivazian, Dana Castro, Ming Chen, Jeffrey Culp, Ken Dower, Joseph Gardner, Steven Hawrylik, Douglas Golenbock, etc.

PLoS One. 2017 Sep 21;12(9):e0184843.

PMID: 28934246

1

Double Knockout of Akt2 and AMPK Accentuates High Fat Diet-Induced Cardiac Anomalies Through a cGAS-STING-mediated Mechanism

Yan Gong, Guangwei Li, Jun Tao, Ne N Wu, Machender R Kandadi, Yaguang Bi, Shuyi Wang, Zhaohui Pei, Jun Ren

Biochim Biophys Acta Mol Basis Dis. 2020 Jun 5;1866(10):165855.

PMID: 32512189

1

In Silico Screening-Based Discovery of Novel Inhibitors of Human Cyclic GMP-AMP Synthase: A Cross-Validation Study of Molecular Docking and Experimental Testing

Wenfeng Zhao, Muya Xiong, Xiaojing Yuan, Minjun Li, Hongbin Sun, Yechun Xu

J Chem Inf Model. 2020 Jun 22;60(6):3265-3276.

PMID: 32459092

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