PF-4 (CXCL4) human

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For Research Use Only | Not For Clinical Use

CAT

IAR42413100

Description	recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
Assay	≥98% (HPLC); ≥98% (SDS-PAGE)
Color	white
Form	lyophilized
Impurity Content	<0.1 EU/μg endotoxin, tested
Size	20μG
Storage Conditions	−20°C

CXCL4L1 and CXCL4 Signaling in Human Lymphatic and Microvascular Endothelial Cells and Activated Lymphocytes: Involvement of Mitogen-Activated Protein (MAP) Kinases, Src and p70S6 Kinase

Katrien Van Raemdonck, Mieke Gouwy, Stefanie Antoinette Lepers, Jo Van Damme, Sofie Struyf

Angiogenesis. 2014 Jul;17(3):631-40.

PMID: 24469069

PF-4/CXCL4 and CXCL4L1 Exhibit Distinct Subcellular Localization and a Differentially Regulated Mechanism of Secretion

Laura Lasagni, Renaud Grepin, Benedetta Mazzinghi, Elena Lazzeri, Claudia Meini, Costanza Sagrinati, Francesco Liotta, Francesca Frosali, Elisa Ronconi, Nathalie Alain-Courtois, Lara Ballerini, Giuseppe Stefano Netti, etc.

Blood. 2007 May 15;109(10):4127-34.

PMID: 17218382

Platelet Factor 4/CXCL4 Induces Phagocytosis and the Generation of Reactive Oxygen Metabolites in Mononuclear Phagocytes Independently of Gi Protein Activation or Intracellular Calcium Transients

Olga Pervushina, Barbara Scheuerer, Norbert Reiling, Lars Behnke, Jens-M Schröder, Brigitte Kasper, Ernst Brandt, Silvia Bulfone-Paus, Frank Petersen

J Immunol. 2004 Aug 1;173(3):2060-7.

PMID: 15265941

Platelets Release CXCL4L1, a Nonallelic Variant of the Chemokine Platelet factor-4/CXCL4 and Potent Inhibitor of Angiogenesis

Sofie Struyf, Marie D Burdick, Paul Proost, Jo Van Damme, Robert M Strieter

Circ Res. 2004 Oct 29;95(9):855-7.

PMID: 15459074

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