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PF-514273

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For Research Use Only | Not For Clinical Use
CATAP851728604
CAS851728-60-4
MDL NumberMFCD12032112
Molecular Weight452.28
InChI KeyFJMQJSUOOGOWBD-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: >5 mg/mL (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

Discovery of 2-(2-chlorophenyl)-3-(4-chlorophenyl)-7-(2,2-difluoropropyl)-6,7-dihydro-2H-pyrazolo[3,4-f][1,4]oxazepin-8(5H)-one (PF-514273), a Novel, Bicyclic Lactam-Based cannabinoid-1 Receptor Antagonist for the Treatment of Obesity

Robert L Dow, Philip A Carpino, John R Hadcock, Shawn C Black, Philip A Iredale, Paul DaSilva-Jardine, Steven R Schneider, Ernest S Paight, David A Griffith, Dennis O Scott, Rebecca E O'Connor, Chudy I Nduaka

J Med Chem. 2009 May 14;52(9):2652-5.

PMID: 19351113

1

Effects of the Novel Cannabinoid CB1 Receptor Antagonist PF 514273 on the Acquisition and Expression of Ethanol Conditioned Place Preference

Melanie M Pina, Christopher L Cunningham

Alcohol. 2014 Aug;48(5):427-31.

PMID: 24954022

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