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PF-562,271

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For Research Use Only | Not For Clinical Use
CATAP939791385
CAS939791-38-5
MDL NumberMFCD14105612
Molecular Weight665.66
Description≥98% (HPLC)
SolubilityDMSO: 2 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to brown
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Antitumor Activity and Pharmacology of a Selective Focal Adhesion Kinase Inhibitor, PF-562,271

Walter Gregory Roberts, Ethan Ung, Pamela Whalen, Beth Cooper, Catherine Hulford, Christofer Autry, Daniel Richter, Earling Emerson, Jing Lin, John Kath, Kevin Coleman, Lili Yao, Luis Martinez-Alsina, Marianne Lorenzen, etc.

Cancer Res. 2008 Mar 15;68(6):1935-44.

PMID: 18339875

1

Bioluminescent Imaging Study: FAK Inhibitor, PF-562,271, Preclinical Study in PC3M-luc-C6 Local Implant and Metastasis Xenograft Models

Haihao Sun, Stephen Pisle, Erin R Gardner, William D Figg

Cancer Biol Ther. 2010 Jul 1;10(1):38-43.

PMID: 20495381

1

Inhibition of Focal Adhesion Kinase by PF-562,271 Inhibits the Growth and Metastasis of Pancreatic Cancer Concomitant With Altering the Tumor Microenvironment

Jayme B Stokes, Sara J Adair, Jill K Slack-Davis, Dustin M Walters, Robert W Tilghman, E Dan Hershey, Bryce Lowrey, Keena S Thomas, Amy H Bouton, Rosa F Hwang, Edward B Stelow, J Thomas Parsons, Todd W Bauer

Mol Cancer Ther. 2011 Nov;10(11):2135-45.

PMID: 21903606

1

Sunitinib and PF-562,271 (FAK/Pyk2 Inhibitor) Effectively Block Growth and Recovery of Human Hepatocellular Carcinoma in a Rat Xenograft Model

Cedo M Bagi, James Christensen, Darrel P Cohen, Walter G Roberts, Dean Wilkie, Terri Swanson, Theresa Tuthill, Catharine J Andresen

Cancer Biol Ther. 2009 May;8(9):856-65.

PMID: 19458500

1

The Focal Adhesion Kinase Inhibitor PF-562,271 Impairs Primary CD4+ T Cell Activation

Andrew J Wiemer, Sarah A Wernimont, Thai-Duong Cung, David A Bennin, Hilary E Beggs, Anna Huttenlocher

Biochem Pharmacol. 2013 Sep 15;86(6):770-81.

PMID: 23928188

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