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PF-573228

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For Research Use Only | Not For Clinical Use
CATAP869288642
CAS869288-64-2
MDL NumberMFCD11519967
Molecular Weight491.49
InChI KeyHESLKTSGTIBHJU-UHFFFAOYSA-N
Description≥95% (HPLC)
SolubilityDMSO: ≥20 mg/mL
Assay≥95% (HPLC)
Colorwhite to off-white
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Characterization of in Vitro Metabolism of Focal Adhesion Kinase Inhibitors by LC/MS/MS

Quan Chi, Ling Wang, Dong Xie, Xian Wang

J Pharm Biomed Anal. 2019 May 10;168:163-173.

PMID: 30807921

1

Focal Adhesion Kinase a Potential Therapeutic Target for Pancreatic Cancer and Malignant Pleural Mesothelioma

Rajani Kanteti, Tamara Mirzapoiazova, Jacob J Riehm, Immanuel Dhanasingh, Bolot Mambetsariev, Jiale Wang, Prakash Kulkarni, Garima Kaushik, Parthasarathy Seshacharyulu, Moorthy P Ponnusamy, Hedy L Kindler, etc.

Cancer Biol Ther. 2018 Apr 3;19(4):316-327.

PMID: 29303405

1

FUS-CHOP Promotes Invasion in Myxoid Liposarcoma Through a SRC/FAK/RHO/ROCK-Dependent Pathway

Juan Tornin, Francisco Hermida-Prado, Ranjit Singh Padda, M Victoria Gonzalez, Carlos Alvarez-Fernandez, Veronica Rey, Lucia Martinez-Cruzado, Oscar Estupiñan, Sofia T Menendez, Lucia Fernandez-Nevado, etc.

Neoplasia. 2018 Jan;20(1):44-56.

PMID: 29190494

1

Inhibiting Focal Adhesion Kinase (FAK) Blocks IL-4 Induced VCAM-1 Expression and Eosinophil Recruitment in Vitro and in Vivo

Gurpreet K Aulakh, Björn Petri, Katarzyna M Wojcik, Pina Colarusso, James J Lee, Kamala D Patel

J Leukoc Biol. 2018 Jul;104(1):147-158.

PMID: 29633338

1

Long Non-Coding RNA (lncRNA) Transcriptional Landscape in Breast Cancer Identifies LINC01614 as Non-Favorable Prognostic Biomarker Regulated by TGFβ and Focal Adhesion Kinase (FAK) Signaling

Radhakrishnan Vishnubalaji, Hibah Shaath, Eyad Elkord, Nehad M Alajez

Cell Death Discov. 2019 Jun 24;5:109.

PMID: 31263577

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