CAS 950912-80-8 PF-670462 - Analytical Products / Alfa Chemistry

CAT	AP950912808
CAS	950912-80-8
Structure
Molecular Weight	410.32

Description	≥98% (HPLC)
Solubility	H2O: 2 mg/mL, clear (warmed)
Assay	≥98% (HPLC)
Color	white to beige
Form	powder
Size	5MG, 25MG
Storage Conditions	2-8°C

1

Casein Kinase 1 Is a Therapeutic Target in Chronic Lymphocytic Leukemia

Pavlina Janovska, Jan Verner, Jiri Kohoutek, Lenka Bryjova, Michaela Gregorova, Marta Dzimkova, Hana Skabrahova, Tomasz Radaszkiewicz, Petra Ovesna, Olga Vondalova Blanarova, Tereza Nemcova, Zuzana Hoferova, etc.

Blood. 2018 Mar 15;131(11):1206-1218.

PMID: 29317454

1

Chronic Treatment With a Selective Inhibitor of Casein Kinase I delta/epsilon Yields Cumulative Phase Delays in Circadian Rhythms

Jeffrey Sprouse, Linda Reynolds, Robin Kleiman, Barbara Tate, Terri A Swanson, Gary E Pickard

Psychopharmacology (Berl). 2010 Jul;210(4):569-76.

PMID: 20407760

1

Entrainment of Disrupted Circadian Behavior Through Inhibition of Casein Kinase 1 (CK1) Enzymes

Qing-Jun Meng, Elizabeth S Maywood, David A Bechtold, Wei-Qun Lu, Jian Li, Julie E Gibbs, Sandrine M Dupré, Johanna E Chesham, Francis Rajamohan, John Knafels, Blossom Sneed, Laura E Zawadzke, Jeffrey F Ohren, etc.

Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15240-5.

PMID: 20696890

1

Inhibition of Casein Kinase 1δ/εimproves Cognitive-Affective Behavior and Reduces Amyloid Load in the APP-PS1 Mouse Model of Alzheimer's Disease

S Sundaram, S Nagaraj, H Mahoney, A Portugues, W Li, K Millsaps, J Faulkner, A Yunus, C Burns, C Bloom, M Said, L Pinto, S Azam, M Flores, A Henriksen, J Gamsby, D Gulick

Sci Rep. 2019 Sep 24;9(1):13743.

PMID: 31551449

1

Therapeutic Targeting of Casein Kinase 1δ/ε in an Alzheimer's Disease Mouse Model

Paula Adler, Janice Mayne, Krystal Walker, Zhibin Ning, Daniel Figeys

J Proteome Res. 2019 Sep 6;18(9):3383-3393.

PMID: 31334659

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