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PF-8380

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For Research Use Only | Not For Clinical Use
CATAP1144035539
CAS1144035-53-9
Structure
Molecular Weight478.33
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

Autotaxin Inhibition With PF-8380 Enhances the Radiosensitivity of Human and Murine Glioblastoma Cell Lines

Sandeep R Bhave, David Y A Dadey, Rowan M Karvas, Daniel J Ferraro, Rama P Kotipatruni, Jerry J Jaboin, Andrew N Hallahan, Todd A Dewees, Amanda G Linkous, Dennis E Hallahan, Dinesh Thotala

Front Oncol. 2013 Sep 17;3:236.

PMID: 24062988

1

Inhibition of Autotaxin Alleviates Inflammation and Increases the Expression of Sodium-Dependent Glucose Cotransporter 1 and Na

Peijian He, Abedul Haque, Songbai Lin, Fabio Cominelli, C Chris Yun

Am J Physiol Gastrointest Liver Physiol. 2018 Nov 1;315(5):G762-G771.

PMID: 30118349

1

Lysophosphatidic Acid Receptors (LPARs): Potential Targets for the Treatment of Neuropathic Pain

María Velasco, Catherine O'Sullivan, Graham K Sheridan

Neuropharmacology. 2017 Feb;113(Pt B):608-617.

PMID: 27059127

1

PF-8380 and Closely Related Analogs: Synthesis and Structure-Activity Relationship Towards Autotaxin Inhibition and Glioma Cell Viability

Patrick-Denis St-Cœur, Dean Ferguson, Pier Morin Jr, Mohamed Touaibia

Arch Pharm (Weinheim). 2013 Feb;346(2):91-7.

PMID: 23300119

1

Pharmacologic Targeting of the ATX/LPA Axis Attenuates Bleomycin-Induced Pulmonary Fibrosis

Ioanna Ninou, Eleanna Kaffe, Stefan Müller, David C Budd, Christopher S Stevenson, Christoph Ullmer, Vassilis Aidinis

Pulm Pharmacol Ther. 2018 Oct;52:32-40.

PMID: 30201409

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