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PF74

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For Research Use Only | Not For Clinical Use
CATAP1352879652
CAS1352879-65-2
Molecular Weight425.52
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

A Novel Phenotype Links HIV-1 Capsid Stability to cGAS-Mediated DNA Sensing

Mohammad Adnan Siddiqui, Akatsuki Saito, Upul D Halambage, Damien Ferhadian, Douglas K Fischer, Ashwanth C Francis, Gregory B Melikyan, Zandrea Ambrose, Christopher Aiken, Masahiro Yamashita

J Virol. 2019 Jul 30;93(16):e00706-19.

PMID: 31167922

1

Compensatory Substitutions in the HIV-1 Capsid Reduce the Fitness Cost Associated With Resistance to a Capsid-Targeting Small-Molecule Inhibitor

Jiong Shi, Jing Zhou, Upul D Halambage, Vaibhav B Shah, Mallori J Burse, Hua Wu, Wade S Blair, Scott L Butler, Christopher Aiken

J Virol. 2015 Jan;89(1):208-19.

PMID: 25320302

1

GS-CA Compounds: First-In-Class HIV-1 Capsid Inhibitors Covering Multiple Grounds

Kamal Singh, Fabio Gallazzi, Kyle J Hill, Donald H Burke, Margaret J Lange, Thomas P Quinn, Ujjwal Neogi, Anders Sönnerborg

Front Microbiol. 2019 Jun 20;10:1227.

PMID: 31312185

1

HIV Capsid Inhibitors Beyond PF74

Carole McArthur, Fabio Gallazzi, Thomas P Quinn, Kamal Singh

Diseases. 2019 Oct 30;7(4):56.

PMID: 31671622

1

Small-molecule Inhibition of Human Immunodeficiency Virus Type 1 Infection by Virus Capsid Destabilization

Jiong Shi, Jing Zhou, Vaibhav B Shah, Christopher Aiken, Kevin Whitby

J Virol. 2011 Jan;85(1):542-9.

PMID: 20962083

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