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PF9601N

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For Research Use Only | Not For Clinical Use
CATAP133845633
CAS133845-63-3
Molecular Weight290.36
Description≥98% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Anti-apoptotic Effect of Mao-B Inhibitor PF9601N [N-(2-propynyl)-2-(5-benzyloxy-indolyl) Methylamine] Is Mediated by p53 Pathway Inhibition in MPP+-treated SH-SY5Y Human Dopaminergic Cells

Elisenda Sanz, Albert Quintana, Valentina Battaglia, Antonio Toninello, Juan Hidalgo, Santiago Ambrosio, Massimo Valoti, Jose Luis Marco, Keith F Tipton, Mercedes Unzeta

J Neurochem. 2008 Jun 1;105(6):2404-17.

PMID: 18331475

1

ASS234, As a New Multi-Target Directed Propargylamine for Alzheimer's Disease Therapy

José Marco-Contelles, Mercedes Unzeta, Irene Bolea, Gerard Esteban, Rona R Ramsay, Alejandro Romero, Ricard Martínez-Murillo, M Carmo Carreiras, Lhassane Ismaili

Front Neurosci. 2016 Jun 28;10:294.

PMID: 27445665

1

CYP-dependent Metabolism of PF9601N, a New Monoamine oxidase-B Inhibitor, by C57BL/6 Mouse and Human Liver Microsomes

Stefania Dragoni, Giada Materozzi, Federica Pessina, Maria Frosini, José Luis Marco, Mercedes Unzeta, Giampietro Sgaragli, Massimo Valoti

J Pharm Pharm Sci. 2007;10(4):473-85.

PMID: 18261369

1

Neuroprotective Effects of the MAO-B Inhibitor, PF9601N, in an in Vivo Model of Excitotoxicity

Irene Bolea, Maria Alessandra Colivicchi, Chiara Ballini, José Marco-Contelles, Keith Francis Tipton, Mercedes Unzeta, Laura Della Corte

CNS Neurosci Ther. 2014 Jul;20(7):641-50.

PMID: 24767579

1

Novel MAO-B Inhibitors: Potential Therapeutic Use of the Selective MAO-B Inhibitor PF9601N in Parkinson's Disease

Mercedes Unzeta, Elisenda Sanz

Int Rev Neurobiol. 2011;100:217-36.

PMID: 21971010

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