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PFK15

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For Research Use Only | Not For Clinical Use
CATAP4382632
CAS4382-63-2
Molecular Weight260.29
Description≥98% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Blockage of Glycolysis by Targeting PFKFB3 Suppresses Tumor Growth and Metastasis in Head and Neck Squamous Cell Carcinoma

Hui-Min Li, Jie-Gang Yang, Zhuo-Jue Liu, Wei-Ming Wang, Zi-Li Yu, Jian-Gang Ren, Gang Chen, Wei Zhang, Jun Jia

J Exp Clin Cancer Res. 2017 Jan 7;36(1):7.

PMID: 28061878

1

Inhibition of 6-phosphofructo-2-kinase Suppresses Fibroblast-Like Synoviocytes-Mediated Synovial Inflammation and Joint Destruction in Rheumatoid Arthritis

Yaoyao Zou, Shan Zeng, Mingcheng Huang, Qian Qiu, Youjun Xiao, Maohua Shi, Zhongping Zhan, Liuqin Liang, Xiuyan Yang, Hanshi Xu

Br J Pharmacol. 2017 May;174(9):893-908.

PMID: 28239846

1

PFK15, a PFKFB3 Antagonist, Inhibits Autophagy and Proliferation in Rhabdomyosarcoma Cells

Chunhui Wang, Jianghong Qu, Siyuan Yan, Quan Gao, Sibin Hao, Dongsheng Zhou

Int J Mol Med. 2018 Jul;42(1):359-367.

PMID: 29620138

1

Targeting 6-phosphofructo-2-kinase (PFKFB3) as a Therapeutic Strategy Against Cancer

Brian F Clem, Julie O'Neal, Gilles Tapolsky, Amy L Clem, Yoannis Imbert-Fernandez, Daniel A Kerr 2nd, Alden C Klarer, Rebecca Redman, Donald M Miller, John O Trent, Sucheta Telang, Jason Chesney

Mol Cancer Ther. 2013 Aug;12(8):1461-70.

PMID: 23674815

1

The Synergistic Effect of PFK15 With Metformin Exerts Anti-Myeloma Activity via PFKFB3

Xinling Liu, Yi Zhao, Enfan Zhang, Haimeng Yan, Ning Lv, Zhen Cai

Biochem Biophys Res Commun. 2019 Jul 23;515(2):332-338.

PMID: 31153642

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