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Phaclofen

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For Research Use Only | Not For Clinical Use
CATAP114012123
CAS114012-12-3
Structure
MDL NumberMFCD00069328
Molecular Weight249.63
InChI KeyVSGNGLJPOGUDON-UHFFFAOYSA-N
Descriptionsolid
Solubility0.1 M HCl: 13.3 mg/mL; methanol: 19.3 mg/mL; DMSO: insoluble
Colorwhite
Formsolid
Impurity Content≥97% (NMR)
Size5MG, 25MG, 100MG
1

A New Alcohol Antagonist: Phaclofen

A M Allan, R A Harris

Life Sci. 1989;45(19):1771-9.

PMID: 2556616

1

GABAB Antagonists: Resolution, Absolute Stereochemistry, and Pharmacology of (R)- And (S)-phaclofen

K Frydenvang, J J Hansen, P Krogsgaard-Larsen, A Mitrovic, H Tran, C A Drew, G A Johnston

Chirality. 1994;6(7):583-9.

PMID: 7986672

1

Phaclofen Antagonizes the Antinociceptive but Not the Sedative Effects of (-)-Baclofen

C De Luca, M Massotti

Prog Neuropsychopharmacol Biol Psychiatry. 1990;14(4):597-607.

PMID: 2173023

1

Phaclofen Antagonizes the Depressant Effect of Baclofen on Spinal Reflex Transmission in Rats

U Wüllner, T Klockgether, K H Sontag

Brain Res. 1989 Sep 4;496(1-2):341-4.

PMID: 2804645

1

Phaclofen-sensitive GABA-B Receptors Do Not Mediate Excitatory Effects of Baclofen on Gastric Secretion

C Blandizzi, M C Bernardini, G Natale, M Del Tacca

Pharmacology. 1991;42(3):128-34.

PMID: 1647534

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