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PI-103 - CAS 371935-74-9

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For Research Use Only | Not For Clinical Use
CATAP371935749
CAS371935-74-9
Structure
Molecular Weight348.36
DescriptionA cell-permeable pyridinylfuranopyrimidine compound that acts as a potent and ATP-competitive inhibitor of DNA-PK, PI3-K, and mTOR.
SolubilityDMSO: 5 mg/mL
Assay≥97% (HPLC)
Colorwhite
Formsolid; protect from light
Size1MG, 5MG
Storage Conditions-20C
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Crystal Structures of PI3Kα Complexed With PI103 and Its Derivatives: New Directions for Inhibitors Design

Yanlong Zhao, Xi Zhang, Yingyi Chen, Shaoyong Lu, Yuefeng Peng, Xiang Wang, Chengliang Guo, Aiwu Zhou, Jingmiao Zhang, Yu Luo, QianCheng Shen, Jian Ding, Linghua Meng, Jian Zhang

ACS Med Chem Lett. 2013 Dec 10;5(2):138-42.

PMID: 24900786

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