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Pifithrin-μ

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For Research Use Only | Not For Clinical Use
CATAP64984312-A
CAS64984-31-2
Structure
MDL NumberMFCD00181531
Molecular Weight181.21
InChI KeyZZUZYEMRHCMVTB-UHFFFAOYSA-N
Description≥97% (HPLC), solid
SolubilityDMSO: soluble >10 mg/mL, clear; H2O: insoluble
Assay≥97% (HPLC)
Formsolid
Size5MG, 10MG
Storage Conditions2-8°C
1

Neuroprotection With the P53-Inhibitor Pifithrin-μ After Cardiac Arrest in a Rodent Model

Michael Glas, Tamara Frick, Dirk Springe, Alessandro Putzu, Patrick Zuercher, Denis Grandgirard, Stephen L Leib, Stephan M Jakob, Jukka Takala, Matthias Haenggi

Shock. 2018 Feb;49(2):229-234.

PMID: 28562478

1

Pifithrin-μ Attenuates Acute Sickness Response to Lipopolysaccharide in C57BL/6J Mice

Rongping Zhang, Jili Wang, Yanling Hu, Xu Lu, Bo Jiang, Wei Zhang, Chao Huang

Pharmacology. 2016;97(5-6):245-50.

PMID: 26881748

1

Pifithrin-μ Induces Necroptosis Through Oxidative Mitochondrial Damage but Accompanies Epithelial-Mesenchymal Transition-Like Phenomenon in Malignant Mesothelioma Cells Under Lactic Acidosis

Yoon-Jin Lee, Kwan-Sik Park, Su-Hak Heo, Hae-Seon Nam, Moon-Kyun Cho, Sang-Han Lee

Arch Pharm Res. 2019 Oct;42(10):890-901.

PMID: 31428976

1

Pifithrin-μ Modulates Microglial Activation and Promotes Histological Recovery Following Spinal Cord Injury

Michael D Caponegro, Luisa F Torres, Cyrus Rastegar, Nisha Rath, Maria E Anderson, John K Robinson, Stella E Tsirka

CNS Neurosci Ther. 2019 Feb;25(2):200-214.

PMID: 29962076

1

Pifithrin-μ Prevents Cisplatin-Induced Chemobrain by Preserving Neuronal Mitochondrial Function

Gabriel S Chiu, Magdalena A Maj, Sahar Rizvi, Robert Dantzer, Elisabeth G Vichaya, Geoffroy Laumet, Annemieke Kavelaars, Cobi J Heijnen

Cancer Res. 2017 Feb 1;77(3):742-752.

PMID: 27879267

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