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PK-THPP

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For Research Use Only | Not For Clinical Use
CATAP1332454075
CAS1332454-07-5
MDL NumberMFCD28396418
Molecular Weight468.59
InChI KeyCJZGRIRZVHNUSM-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityH2O: 10 mg/mL, clear; DMSO: 2 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

A1899, PK-THPP, ML365, and Doxapram Inhibit Endogenous TASK Channels and Excite Calcium Signaling in Carotid Body type-1 Cells

Peadar B O'Donohoe, Nicky Huskens, Philip J Turner, Jaideep J Pandit, Keith J Buckler

Physiol Rep. 2018 Sep;6(19):e13876.

PMID: 30284397

1

Abnormalities of Serotonergic Neurotransmission in Animal Models of SUDEP

Hua-Jun Feng, Carl L Faingold

Epilepsy Behav. 2017 Jun;71(Pt B):174-180.

PMID: 26272185

1

Spinal TASK-1 and TASK-3 Modulate Inflammatory and Neuropathic Pain

Guadalupe García, Roxana Noriega-Navarro, Vladimir A Martínez-Rojas, Erika J Gutiérrez-Lara, Norma Oviedo, Janet Murbartián

Eur J Pharmacol. 2019 Nov 5;862:172631.

PMID: 31472119

1

Structure/Activity Analysis of TASK-3 Channel Antagonists Based on a 5,6,7,8 tetrahydropyrido[4,3-d]pyrimidine

David Ramírez, Mauricio Bedoya, Aytug K Kiper, Susanne Rinné, Samuel Morales-Navarro, Erix W Hernández-Rodríguez, Francisco V Sepúlveda, Niels Decher, Wendy González

Int J Mol Sci. 2019 May 7;20(9):2252.

PMID: 31067753

1

TASK-1 (KCNK3) and TASK-3 (KCNK9) Tandem Pore Potassium Channel Antagonists Stimulate Breathing in Isoflurane-Anesthetized Rats

Joseph F Cotten

Anesth Analg. 2013 Apr;116(4):810-6.

PMID: 23460565

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