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PK11007

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For Research Use Only | Not For Clinical Use
CATAP38275342
CAS38275-34-2
Structure
MDL NumberMFCD00507244
Molecular Weight236.63
Description≥98% (HPLC)
SolubilityH2O: 10 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

2-Sulfonylpyrimidines: Mild Alkylating Agents With Anticancer Activity Toward p53-compromised Cells

Matthias R Bauer, Andreas C Joerger, Alan R Fersht

Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):E5271-80.

PMID: 27551077

1

Mutant p53 as a Target for Cancer Treatment

Michael J Duffy, Naoise C Synnott, John Crown

Eur J Cancer. 2017 Sep;83:258-265.

PMID: 28756138

1

Mutant p53 as a Therapeutic Target for the Treatment of Triple-Negative Breast Cancer: Preclinical Investigation With the anti-p53 Drug, PK11007

Naoise C Synnott, Matthias R Bauer, Stephen Madden, Alyson Murray, Rut Klinger, Norma O'Donovan, Darran O'Connor, William M Gallagher, John Crown, Alan R Fersht, Michael J Duffy

Cancer Lett. 2018 Feb 1;414:99-106.

PMID: 29069577

1

Mutant p53 in Breast Cancer: Potential as a Therapeutic Target and Biomarker

Michael J Duffy, Naoise C Synnott, John Crown

Breast Cancer Res Treat. 2018 Jul;170(2):213-219.

PMID: 29564741

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