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PKG Inhibitor

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For Research Use Only | Not For Clinical Use
CATIAR42415609
Molecular Weight943.11
DescriptionThe PKG Inhibitor controls the biological activity of PKG. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
Solubilitywater: 1 mg/mL
Assay≥95% (HPLC)
Formlyophilized; desiccated
Size1MG
Storage Conditions-20C
1

Angiotensin-(1-7) Induced Vascular Relaxation in Spontaneously Hypertensive Rats

Feng Zhang, Haiyang Tang, Shuo Sun, Yuru Luo, Xingsheng Ren, Aidong Chen, Yu Xu, Peng Li, Ying Han

Nitric Oxide. 2019 Jul 1;88:1-9.

PMID: 30880106

1

Essential Role of the cGMP/PKG Signaling Pathway in Regulating the Proliferation and Survival of Human Renal Carcinoma Cells

Yu Ren, Jianjian Zheng, Xuping Yao, Guobin Weng, Ling Wu

Int J Mol Med. 2014 Nov;34(5):1430-8.

PMID: 25244411

1

PDE5 Inhibitor Promotes Melanin Synthesis Through the PKG Pathway in B16 Melanoma Cells

Xiaodong Zhang, Guirui Yan, Jun Ji, Jingwei Wu, Xiaoyun Sun, Jingshan Shen, Hualiang Jiang, Heyao Wang

J Cell Biochem. 2012 Aug;113(8):2738-43.

PMID: 22441938

1

The Anti-Diabetic Drug Dapagliflozin Induces Vasodilation via Activation of PKG and Kv Channels

Hongliang Li, Sung Eun Shin, Mi Seon Seo, Jin Ryeol An, Il-Whan Choi, Won-Kyo Jung, Amy L Firth, Dae-Sung Lee, Mi-Jin Yim, Grace Choi, Jeong Min Lee, Sung Hun Na, Won Sun Park

Life Sci. 2018 Mar 15;197:46-55.

PMID: 29409796

1

The bradykinin-cGMP-PKG Pathway Augments Insulin Sensitivity via Upregulation of MAPK phosphatase-5 and Inhibition of JNK

María E Frigolet, Garry Thomas, Kristin Beard, Huogen Lu, Lijiang Liu, I George Fantus

Am J Physiol Endocrinol Metab. 2017 Sep 1;313(3):E321-E334.

PMID: 28679626

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