0

PKI-166

INQUIRY Add to cart
For Research Use Only | Not For Clinical Use
CATAP187724614
CAS187724-61-4
MDL NumberMFCD09970842
Molecular Weight330.38
InChI KeyXRYJULCDUUATMC-CYBMUJFWSA-N
Description≥98% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Epidermal Growth Factor Receptor Inhibitor PKI-166 Governs Cardiovascular Protection Without Beneficial Effects on the Kidney in Hypertensive 5/6 Nephrectomized Rats

Nadir Ulu, Gemma M Mulder, Peter Vavrinec, Sjoerd W Landheer, Basak Duman-Dalkilic, Hakan Gurdal, Maaike Goris, Marry Duin, Richard P E van Dokkum, Hendrik Buikema, Harry van Goor, Robert H Henning

J Pharmacol Exp Ther. 2013 Jun;345(3):393-403.

PMID: 23528611

1

Growth Inhibitory Effects of the Dual ErbB1/ErbB2 Tyrosine Kinase Inhibitor PKI-166 on Human Prostate Cancer Xenografts

Ingo K Mellinghoff, Chris Tran, Charles L Sawyers

Cancer Res. 2002 Sep 15;62(18):5254-9.

PMID: 12234993

1

Optimization for the Blockade of Epidermal Growth Factor Receptor Signaling for Therapy of Human Pancreatic Carcinoma

C C Solorzano, C H Baker, R Tsan, P Traxler, P Cohen, E Buchdunger, J J Killion, I J Fidler

Clin Cancer Res. 2001 Aug;7(8):2563-72.

PMID: 11489840

1

PKI 166 Induced Redox Signalling and Apoptosis Through Activation of p53, MAP Kinase and Caspase Pathway in Epidermoid Carcinoma

Subhasis Das, Kaushik Kumar Dey, Rashmi Bharti, Sujata MaitiChoudhury, Sukumar Maiti, Mahitosh Mandal

J Exp Ther Oncol. 2012;10(2):139-53.

PMID: 23350354

1

Podocyte Hypertrophy Precedes Apoptosis Under Experimental Diabetic Conditions

Sun Ha Lee, Sung Jin Moon, Jisun Paeng, Hye-Young Kang, Bo Young Nam, Seonghun Kim, Chan Ho Kim, Mi Jung Lee, Hyung Jung Oh, Jung Tak Park, Seung Hyeok Han, Tae-Hyun Yoo, Shin-Wook Kang

Apoptosis. 2015 Aug;20(8):1056-71.

PMID: 25953318

  • Verification code
Contact Us

Send Us a Request

What is your specific need? We will do everything we can to meet your expectations.
Online Inquiry

Online Inquiry

For any inquiry, question or recommendation, please call: or fill out the following form.

  • Verification code

Head Office

  • Tel:
  • Email:

Follow us on

qrcode