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PP1

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For Research Use Only | Not For Clinical Use
CATAP172889268-A
CAS172889-26-8
Structure
MDL NumberMFCD01076570
Molecular Weight281.36
InChI KeyZVPDNRVYHLRXLX-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: >20 mg/mL
Assay≥98% (HPLC)
Colorwhite to off-white
Formpowder
Size5MG, 25MG
Storage Conditionsroom temp
1

A PP1-PP2A Phosphatase Relay Controls Mitotic Progression

Agnes Grallert, Elvan Boke, Anja Hagting, Ben Hodgson, Yvonne Connolly, John R Griffiths, Duncan L Smith, Jonathon Pines, Iain M Hagan

Nature. 2015 Jan 1;517(7532):94-98.

PMID: 25487150

1

A Substrate-Trapping Strategy for Protein Phosphatase PP1 Holoenzymes Using Hypoactive Subunit Fusions

Dan Wu, Veerle De Wever, Rita Derua, Claudia Winkler, Monique Beullens, Aleyde Van Eynde, Mathieu Bollen

J Biol Chem. 2018 Sep 28;293(39):15152-15162.

PMID: 30115685

1

ASPP Proteins Discriminate Between PP1 Catalytic Subunits Through Their SH3 Domain and the PP1 C-tail

M Teresa Bertran, Stéphane Mouilleron, Yanxiang Zhou, Rakhi Bajaj, Federico Uliana, Ganesan Senthil Kumar, Audrey van Drogen, Rebecca Lee, Jennifer J Banerjee, Simon Hauri, Nicola O'Reilly, Matthias Gstaiger, etc.

Nat Commun. 2019 Feb 15;10(1):771.

PMID: 30770806

1

Aurora B Opposes PP1 Function in Mitosis by Phosphorylating the Conserved PP1-binding RVxF Motif in PP1 Regulatory Proteins

Isha Nasa, Scott F Rusin, Arminja N Kettenbach, Greg B Moorhead

Sci Signal. 2018 May 15;11(530):eaai8669.

PMID: 29764992

1

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation

Matthias Weith, Jonas Seiler, Johannes van den Boom, Matthias Kracht, Julia Hülsmann, Ivana Primorac, Javier Del Pino Garcia, Farnusch Kaschani, Markus Kaiser, Andrea Musacchio, Mathieu Bollen, Hemmo Meyer

Mol Cell. 2018 Nov 15;72(4):766-777.e6.

PMID: 30344098

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