CAS 172889-27-9 PP2 - CAS 172889-27-9 - Analytical Products / Alfa Chemistry

CAT	AP172889279
CAS	172889-27-9
Structure
Molecular Weight	301.77

Description	PP2, CAS 172889-27-9, is a potent, reversible, ATP-competitive, inhibitor of the Src family of protein tyrosine kinases (IC₅₀ = 4, 5, 5, &100 nM for p56lck, p59fynT, Hck, & Src, respectively).
Solubility	DMSO: 20 mg/mL
Assay	≥95% (HPLC)
Color	off-white
Form	solid
Size	1MG, 5MG
Storage Conditions	-20C

1

Elucidation of the Roles of the Src Kinases in Pancreatic Acinar Cell Signaling

Bernardo Nuche-Berenguer, Paola Moreno, R T Jensen

J Cell Biochem. 2015 Jan;116(1):22-36.

PMID: 25079913

1

Ocular Hypotensive Efficacy of Src-family Tyrosine Kinase Inhibitors via Different Cellular Actions From Rock Inhibitors

Tomoko Kirihara, Atsushi Shimazaki, Masatsugu Nakamura, Nobuaki Miyawaki

Exp Eye Res. 2014 Feb;119:97-105.

PMID: 24321889

1

Role and Regulation of Abelson Tyrosine Kinase in Crk-associated substrate/profilin-1 Interaction and Airway Smooth Muscle Contraction

Yinna Wang, Alyssa C Rezey, Ruping Wang, Dale D Tang

Respir Res. 2018 Jan 5;19(1):4.

PMID: 29304860

1

Src and Cas Are Essentially but Differentially Involved in Angiotensin II-stimulated Migration of Vascular Smooth Muscle Cells via Extracellular Signal-Regulated Kinase 1/2 and c-Jun NH2-terminal Kinase Activation

Moe Kyaw, Masanori Yoshizumi, Koichiro Tsuchiya, Shoji Kagami, Yuki Izawa, Yoshiko Fujita, Nermin Ali, Yasuhisa Kanematsu, Kazunori Toida, Kazunori Ishimura, Toshiaki Tamaki

Mol Pharmacol. 2004 Apr;65(4):832-41.

PMID: 15044612

1

Src Regulates Phorbol 12-myristate 13-acetate-activated PKC-induced Migration via Cas/Crk/Rac1 Signaling Pathway in Glioblastoma Cells

Naoko Nomura, Motohiro Nomura, Kazuhisa Sugiyama, Jun-Ichiro Hamada

Int J Mol Med. 2007 Oct;20(4):511-9.

PMID: 17786281

* Products or Services Interested: PP2 - CAS 172889-27-9 (172889-27-9)
* Your question
* Name
* Email
Verification Code