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Pristimerin

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For Research Use Only | Not For Clinical Use
CATAP1258840
CAS1258-84-0
Structure
MDL NumberMFCD01711331
Molecular Weight464.64
InChI KeyJFACETXYABVHFD-WXPPGMDDSA-N
SolubilityDMSO: ≥5 mg/mL
Assay≥98% (HPLC)
Colororange
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

A Promising Natural Product, Pristimerin, Results in Cytotoxicity Against Breast Cancer Stem Cells in Vitro and Xenografts in Vivo Through Apoptosis and an Incomplete Autopaghy in Breast Cancer

Buse Cevatemre, Merve Erkısa, Nazlihan Aztopal, Didem Karakas, Pınar Alper, Chrisiida Tsimplouli, Evangelia Sereti, Konstantinos Dimas, Elif I Ikitimur Armutak, Ebru Gurel Gurevin, Ayca Uvez, Mattia Mori, etc.

Pharmacol Res. 2018 Mar;129:500-514.

PMID: 29197639

1

Anti-Cancer Effects of Pristimerin and the Mechanisms: A Critical Review

Jia-Jun Li, Yan-Yan Yan, Hong-Mei Sun, Yun Liu, Chao-Yue Su, Hu-Biao Chen, Jian-Ye Zhang

Front Pharmacol. 2019 Jul 12;10:746.

PMID: 31354475

1

Combination of Pristimerin and Paclitaxel Additively Induces Autophagy in Human Breast Cancer Cells via ERK1/2 Regulation

Younju Lee, Jinuk Na, Myung Sun Lee, Eun Young Cha, Ji Young Sul, Jun Beom Park, Jin Sun Lee

Mol Med Rep. 2018 Nov;18(5):4281-4288.

PMID: 30221728

1

Pristimerin Induces Apoptosis and Autophagy via Activation of ROS/ASK1/JNK Pathway in Human Breast Cancer in Vitro and in Vivo

Qun Zhao, Yingxiang Liu, Jing Zhong, Yun Bi, Yongqiang Liu, Ziting Ren, Xiang Li, Junjun Jia, Mengting Yu, Xianjun Yu

Cell Death Discov. 2019 Aug 5;5:125.

PMID: 31396402

1

Pristimerin Induces Autophagy-Mediated Cell Death in K562 Cells Through the ROS/JNK Signaling Pathway

Yingxiang Liu, Ziting Ren, Xiang Li, Jing Zhong, Yun Bi, Rui Li, Qun Zhao, Xianjun Yu

Chem Biodivers. 2019 Aug;16(8):e1900325.

PMID: 31290253

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