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PRL-3 Inhibitor I

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For Research Use Only | Not For Clinical Use
CATAP893449382
CAS893449-38-2
Structure
MDL NumberMFCD11045303
Molecular Weight485.21
InChI KeyHXNBAOLVPAWYLT-OVCLIPMQSA-N
Description≥98% (HPLC), solid
SolubilityDMSO: >10 mg/mL; H2O: <2 mg/mL
Assay≥98% (HPLC)
Coloryellow
Formsolid
Size5MG
Storage Conditions−20°C
1

IL6 Promotes a STAT3-PRL3 Feedforward Loop via SHP2 Repression in Multiple Myeloma

Phyllis S Y Chong, Jianbiao Zhou, Julia S L Lim, Yan Ting Hee, Jing-Yuan Chooi, Tae-Hoon Chung, Zea Tuan Tan, Qi Zeng, Daniel D Waller, Michael Sebag, Wee-Joo Chng

Cancer Res. 2019 Sep 15;79(18):4679-4688.

PMID: 31337650

1

Non-canonical Activation of β-catenin by PRL-3 Phosphatase in Acute Myeloid Leukemia

Phyllis S Y Chong, Jianbiao Zhou, Jing-Yuan Chooi, Zit-Liang Chan, Sabrina Hui Min Toh, Tuan Zea Tan, Sheena Wee, Jayantha Gunaratne, Qi Zeng, Wee-Joo Chng

Oncogene. 2019 Feb;38(9):1508-1519.

PMID: 30305722

1

Phosphatase of Regenerating liver-3 (PRL-3) Is Overexpressed in Classical Hodgkin Lymphoma and Promotes Survival and Migration

Magnus Aassved Hjort, Håkon Hov, Pegah Abdollahi, Esten Nymoen Vandsemb, Unn-Merete Fagerli, Bendik Lund, Tobias Schmidt Slørdahl, Magne Børset, Torstein Baade Rø

Exp Hematol Oncol. 2018 Apr 10;7:8.

PMID: 29651360

1

PRL-3 Is a Potential Glioblastoma Prognostic Marker and Promotes Glioblastoma Progression by Enhancing MMP7 Through the ERK and JNK Pathways

Nan Mu, Jintao Gu, Nannan Liu, Xiaochang Xue, Zhen Shu, Kuo Zhang, Tonglie Huang, Chu Chu, Wangqian Zhang, Li Gong, Huadong Zhao, Bo Jia, Dakuan Gao, Lei Shang, Wei Zhang, Qingdong Guo

Theranostics. 2018 Feb 7;8(6):1527-1539.

PMID: 29556339

1

STAT3: A Promising Therapeutic Target in Multiple Myeloma

Phyllis S Y Chong, Wee-Joo Chng, Sanjay de Mel

Cancers (Basel). 2019 May 26;11(5):731.

PMID: 31130718

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