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PRMT6 active human

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For Research Use Only | Not For Clinical Use
CATIAR42416114
Descriptionrecombinant, expressed in E. coli, ≥70% (SDS-PAGE)
Assay≥70% (SDS-PAGE)
Formaqueous solution
Size20μG
Storage Conditions−70°C
1

A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases

Mohammad S Eram, Yudao Shen, Magdalena Szewczyk, Hong Wu, Guillermo Senisterra, Fengling Li, Kyle V Butler, H Ümit Kaniskan, Brandon A Speed, Carlo Dela Seña, Aiping Dong, Hong Zeng, Matthieu Schapira, etc.

ACS Chem Biol. 2016 Mar 18;11(3):772-781.

PMID: 26598975

1

Functional Insights From High Resolution Structures of Mouse Protein Arginine Methyltransferase 6

Luc Bonnefond, Johann Stojko, Justine Mailliot, Nathalie Troffer-Charlier, Vincent Cura, Jean-Marie Wurtz, Sarah Cianférani, Jean Cavarelli

J Struct Biol. 2015 Aug;191(2):175-83.

PMID: 26094878

1

Methylation of Histone H3R2 by PRMT6 and H3K4 by an MLL Complex Are Mutually Exclusive

Ernesto Guccione, Christian Bassi, Fabio Casadio, Francesca Martinato, Matteo Cesaroni, Henning Schuchlautz, Bernhard Lüscher, Bruno Amati

Nature. 2007 Oct 18;449(7164):933-7.

PMID: 17898714

1

pUL69 of Human Cytomegalovirus Recruits the Cellular Protein Arginine Methyltransferase 6 via a Domain That Is Crucial for mRNA Export and Efficient Viral Replication

Marco Thomas, Eric Sonntag, Regina Müller, Stefanie Schmidt, Barbara Zielke, Torgils Fossen, Thomas Stamminger

J Virol. 2015 Sep;89(18):9601-15.

PMID: 26178996

1

The Protein Arginine Methyltransferase PRMT6 Inhibits HIV-1 Tat Nucleolar Retention

Alex J Fulcher, Haran Sivakumaran, Hongping Jin, Daniel J Rawle, David Harrich, David A Jans

Biochim Biophys Acta. 2016 Feb;1863(2):254-62.

PMID: 26611710

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