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Progranulin from mouse

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For Research Use Only | Not For Clinical Use
CATIAR42413497
Descriptionrecombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
Assay≥95% (SDS-PAGE)
Formliquid
Size10μG
Storage Conditions−20°C
1

AAV-Mediated Progranulin Delivery to a Mouse Model of Progranulin Deficiency Causes T Cell-Mediated Toxicity

Defne A Amado, Julianne M Rieders, Fortunay Diatta, Pilar Hernandez-Con, Adina Singer, Jordan T Mak, Junxian Zhang, Eric Lancaster, Beverly L Davidson, Alice S Chen-Plotkin

Mol Ther. 2019 Feb 6;27(2):465-478.

PMID: 30559071

1

Genetic Regulation of Neuronal Progranulin Reveals a Critical Role for the Autophagy-Lysosome Pathway

Lisa P Elia, Amanda R Mason, Amela Alijagic, Steven Finkbeiner

J Neurosci. 2019 Apr 24;39(17):3332-3344.

PMID: 30696728

1

Progranulin Gene Therapy Improves Lysosomal Dysfunction and Microglial Pathology Associated With Frontotemporal Dementia and Neuronal Ceroid Lipofuscinosis

Andrew E Arrant, Vincent C Onyilo, Daniel E Unger, Erik D Roberson

J Neurosci. 2018 Feb 28;38(9):2341-2358.

PMID: 29378861

1

Restoring Neuronal Progranulin Reverses Deficits in a Mouse Model of Frontotemporal Dementia

Andrew E Arrant, Anthony J Filiano, Daniel E Unger, Allen H Young, Erik D Roberson

Brain. 2017 May 1;140(5):1447-1465.

PMID: 28379303

1

Retrograde Signaling From Progranulin to Sort1 Counteracts Synapse Elimination in the Developing Cerebellum

Naofumi Uesaka, Manabu Abe, Kohtarou Konno, Maya Yamazaki, Kazuto Sakoori, Takaki Watanabe, Tzu-Huei Kao, Takayasu Mikuni, Masahiko Watanabe, Kenji Sakimura, Masanobu Kano

Neuron. 2018 Feb 21;97(4):796-805.e5.

PMID: 29398357

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