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Protopine

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For Research Use Only | Not For Clinical Use
CATAP130869
CAS130-86-9
Structure
MDL NumberMFCD00022322
Molecular Weight353.37
InChI KeyGPTFURBXHJWNHR-UHFFFAOYSA-N
1

Characterization of the Cytotoxicity of Selected Chelidonium Alkaloids in Rat Hepatocytes

Lan Gao, Hans-Joachim Schmitz, Karl-Heinz Merz, Dieter Schrenk

Toxicol Lett. 2019 Sep 1;311:91-97.

PMID: 31054355

1

Protopine and Allocryptopine Increase mRNA Levels of Cytochromes P450 1A in Human Hepatocytes and HepG2 Cells Independently of AhR

Jiri Vrba, Eva Vrublova, Martin Modriansky, Jitka Ulrichova

Toxicol Lett. 2011 Jun 10;203(2):135-41.

PMID: 21419197

1

Protopine Attenuates Inflammation Stimulated by Carrageenan and LPS via the MAPK/NF-κB Pathway

Md Badrul Alam, Mi-Kyoung Ju, Yoon-Gyung Kwon, Sang Han Lee

Food Chem Toxicol. 2019 Sep;131:110583.

PMID: 31220533

1

Protopine Isolated From Nandina Domestica Induces Apoptosis and Autophagy in Colon Cancer Cells by Stabilizing p53

Younglim Son, Younju An, Jaeyeon Jung, Sora Shin, InWha Park, Jungsug Gwak, Bong Gun Ju, Young-Hwa Chung, MinKyun Na, Sangtaek Oh

Phytother Res. 2019 Jun;33(6):1689-1696.

PMID: 30932278

1

Protopine Protects Mice Against LPS-Induced Acute Kidney Injury by Inhibiting Apoptosis and Inflammation via the TLR4 Signaling Pathway

Beibei Zhang, Mengnan Zeng, Meng Li, Yuxuan Kan, Benke Li, Ruiqi Xu, Yuanyuan Wu, Shengchao Wang, Xiaoke Zheng, Weisheng Feng

Molecules. 2019 Dec 19;25(1):15.

PMID: 31861525

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