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PTC-209

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For Research Use Only | Not For Clinical Use
CATAP315704666
CAS315704-66-6
MDL NumberMFCD02110649
Molecular Weight495.19
InChI KeyXVOOCQSWCCRVDY-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to brown
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Concurrent Targeting of BMI1 and CDK4/6 Abrogates Tumor Growth in Vitro and in Vivo

Ramesh Elango, Radhakrishnan Vishnubalaji, Muthurangan Manikandan, Sarah Ibrahim Binhamdan, Abdul-Aziz Siyal, Yasser A Alshawakir, Musaad Alfayez, Abdullah Aldahmash, Nehad M Alajez

Sci Rep. 2019 Sep 23;9(1):13696.

PMID: 31548560

1

Pharmacological Inhibition of Bmi1 by PTC-209 Impaired Tumor Growth in Head Neck Squamous Cell Carcinoma

Qiong Wang, Zhongwu Li, Yaping Wu, Rong Huang, Yumin Zhu, Wei Zhang, Yanling Wang, Jie Cheng

Cancer Cell Int. 2017 Nov 21;17:107.

PMID: 29200967

1

PTC-209 Anti-Cancer Effects Involved the Inhibition of STAT3 Phosphorylation

Shahrazad Sulaiman, Kholoud Arafat, Rabah Iratni, Samir Attoub

Front Pharmacol. 2019 Oct 21;10:1199.

PMID: 31695609

1

Targeting of BMI-1 With PTC-209 Inhibits Glioblastoma Development

Yu Kong, Chunbo Ai, Feng Dong, Xianyou Xia, Xiujuan Zhao, Chao Yang, Chunsheng Kang, Yan Zhou, Qian Zhao, Xiujing Sun, Xudong Wu

Cell Cycle. 2018;17(10):1199-1211.

PMID: 29886801

1

The BMI1 Inhibitor PTC-209 Is a Potential Compound to Halt Cellular Growth in Biliary Tract Cancer Cells

Christian Mayr, Andrej Wagner, Magdalena Loeffelberger, Daniela Bruckner, Martin Jakab, Frieder Berr, Pietro Di Fazio, Matthias Ocker, Daniel Neureiter, Martin Pichler, Tobias Kiesslich

Oncotarget. 2016 Jan 5;7(1):745-58.

PMID: 26623561

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