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PYR-41

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For Research Use Only | Not For Clinical Use
CATAP418805024
CAS418805-02-4
Structure
Molecular Weight371.30
InChI KeyARGIPZKQJGFSGQ-UKTHLTGXSA-N
Description≥98% (HPLC), powder
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorred to brown
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

Administration of Ubiquitin-Activating Enzyme UBA1 Inhibitor PYR-41 Attenuates Angiotensin II-induced Cardiac Remodeling in Mice

Qing Shu, Song Lai, Xiao-Mei Wang, Yun-Long Zhang, Xiao-Lei Yang, Hai-Lian Bi, Hui-Hua Li

Biochem Biophys Res Commun. 2018 Oct 20;505(1):317-324.

PMID: 30249396

1

Dynamic Regulation of Dynein Localization Revealed by Small Molecule Inhibitors of Ubiquitination Enzymes

Julie K Monda, Iain M Cheeseman

Open Biol. 2018 Sep 26;8(9):180095.

PMID: 30257893

1

PYR-41 and Thalidomide Impair Dendritic Cell Cross-Presentation by Inhibiting Myddosome Formation and Attenuating the Endosomal Recruitments of p97 and Sec61 via NF- κ B Inactivation

Xiang You, Dan Dan Xu, Di Zhang, Jie Chen, Feng Guang Gao

J Immunol Res. 2018 Jul 5;2018:5070573.

PMID: 30069488

1

PYR-41, A Ubiquitin-Activating Enzyme E1 Inhibitor, Attenuates Lung Injury in Sepsis

Shingo Matsuo, Archna Sharma, Ping Wang, Weng-Lang Yang

Shock. 2018 Apr;49(4):442-450.

PMID: 28661933

1

Ubiquitin-activating Enzyme E1 Inhibitor PYR-41 Retards Sperm Enlargement After Fusion to the Egg

Keiichi Yoshida, Woojin Kang, Akihiro Nakamura, Natsuko Kawano, Maito Hanai, Mami Miyado, Yoshitaka Miyamoto, Maki Iwai, Toshio Hamatani, Hidekazu Saito, Kenji Miyado, Akihiro Umezawa

Reprod Toxicol. 2018 Mar;76:71-77.

PMID: 29355596

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