CAS 161796-77-6 R-Omeprazole - Analytical Products / Alfa Chemistry

CAT	AP161796776
CAS	161796-77-6
Structure
Molecular Weight	367.40

Description	United States Pharmacopeia (USP) Reference Standard
Size	15MG

1

A Pharmacokinetic Study Comparing Single and Repeated Oral Doses of 20 Mg and 40 Mg Omeprazole and Its Two Optical Isomers, S-omeprazole (Esomeprazole) and R-omeprazole, in Healthy Subjects

M Hassan-Alin, T Andersson, M Niazi, K Röhss

Eur J Clin Pharmacol. 2005 Jan;60(11):779-84.

PMID: 15578172

1

Association With Polymorphic Marmoset Cytochrome P450 2C19 of in Vivo Hepatic Clearances of Chirally Separated R-omeprazole and S-warfarin Using Individual Marmoset Physiologically Based Pharmacokinetic Models

Takashi Kusama, Akiko Toda, Makiko Shimizu, Shotaro Uehara, Takashi Inoue, Yasuhiro Uno, Masahiro Utoh, Erika Sasaki, Hiroshi Yamazaki

Xenobiotica. 2018 Oct;48(10):1072-1077.

PMID: 29034770

1

Hydroxylation of R(+)- And S(-)-omeprazole After Racemic Dosing Are Different Among the CYP2C19 Genotypes

Hideo Shiohira, Norio Yasui-Furukori, Satoshi Yamada, Tomonori Tateishi, Yumiko Akamine, Tsukasa Uno

Pharm Res. 2012 Aug;29(8):2310-6.

PMID: 22549736

1

Oxidation of R- And S-omeprazole Stereoselectively Mediated by Liver Microsomal Cytochrome P450 2C19 Enzymes From Cynomolgus Monkeys and Common Marmosets

Shotaro Uehara, Mirai Kawano, Norie Murayama, Yasuhiro Uno, Masahiro Utoh, Takashi Inoue, Erika Sasaki, Hiroshi Yamazaki

Biochem Pharmacol. 2016 Nov 15;120:56-62.

PMID: 27641812

1

The (R)-omeprazole Hydroxylation Index Reflects CYP2C19 Activity in Healthy Japanese Volunteers

Satoshi Yamada, Hideo Shiohira, Norio Yasui-Furukori, Tomonori Tateishi, Yumiko Akamine, Tsukasa Uno

Eur J Clin Pharmacol. 2013 Jul;69(7):1423-8.

PMID: 23435615

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