CAS 444912-48-5 (R,S)-AM1241 - Analytical Products / Alfa Chemistry

CAT	AP444912485
CAS	444912-48-5
Structure
MDL Number	MFCD11045986
Molecular Weight	503.33
InChI Key	ZUHIXXCLLBMBDW-UHFFFAOYSA-N

Description	≥98% (HPLC), solid
Solubility	DMSO: ~18 mg/mL at 60 °C
Assay	≥98% (HPLC)
Color	yellow
Form	solid
Size	5MG, 25MG

1

Antinociceptive Effects of Racemic AM1241 and Its Chirally Synthesized Enantiomers: Lack of Dependence Upon Opioid Receptor Activation

Elizabeth J Rahn, Alexander M Zvonok, Alexandros Makriyannis, Andrea G Hohmann

AAPS J. 2010 Jun;12(2):147-57.

PMID: 20127295

1

Interaction of a Cannabinoid-2 Agonist With Tramadol on Nociceptive Thresholds and Immune Responses in a Rat Model of Incisional Pain

Chrysoula C Stachtari, Olympia N Thomareis, Georgia G Tsaousi, Konstantinos A Karakoulas, Foteini I Chatzimanoli, Stavros A Chatzopoulos, Dimitrios G Vasilakos

Am J Ther. Nov/Dec 2016;23(6):e1484-e1492.

PMID: 25370921

1

Selective Activation of Cannabinoid CB2 Receptors Suppresses Neuropathic Nociception Induced by Treatment With the Chemotherapeutic Agent Paclitaxel in Rats

Elizabeth J Rahn, Alexander M Zvonok, Ganesh A Thakur, Atmaram D Khanolkar, Alexandros Makriyannis, Andrea G Hohmann

J Pharmacol Exp Ther. 2008 Nov;327(2):584-91.

PMID: 18664590

1

Self-medication of a Cannabinoid CB2 Agonist in an Animal Model of Neuropathic Pain

Tannia Gutierrez, Jonathon D Crystal, Alexander M Zvonok, Alexandros Makriyannis, Andrea G Hohmann

Pain. 2011 Sep;152(9):1976-87.

PMID: 21550725

1

Species-specific in Vitro Pharmacological Effects of the Cannabinoid Receptor 2 (CB2) Selective Ligand AM1241 and Its Resolved Enantiomers

B Bingham, P G Jones, A J Uveges, S Kotnis, P Lu, V A Smith, S-C Sun, L Resnick, M Chlenov, Y He, B W Strassle, T A Cummons, M J Piesla, J E Harrison, G T Whiteside, J D Kennedy

Br J Pharmacol. 2007 Aug;151(7):1061-70.

PMID: 17549048

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