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Ranirestat

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For Research Use Only | Not For Clinical Use
CATAP147254646
CAS147254-64-6
MDL NumberMFCD00920915
Molecular Weight420.19
InChI KeyQCVNMNYRNIMDKV-QGZVFWFLSA-N
Description≥97% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥97% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

Aldose Reductase Inhibitor Ranirestat Significantly Improves Nerve Conduction Velocity in Diabetic Polyneuropathy: A Randomized Double-Blind Placebo-Controlled Study in Japan

Kenji Sekiguchi, Nobuo Kohara, Masayuki Baba, Tetsuo Komori, Yutaka Naito, Tomihiro Imai, Jo Satoh, Yasuyuki Yamaguchi, Tatsuto Hamatani, Ranirestat Group

J Diabetes Investig. 2019 Mar;10(2):466-474.

PMID: 29975462

1

Diabetic Neuropathy and Oxidative Stress: Therapeutic Perspectives

Asieh Hosseini, Mohammad Abdollahi

Oxid Med Cell Longev. 2013;2013:168039.

PMID: 23738033

1

Ranirestat Improved Nerve Conduction Velocities, Sensory Perception, and Intraepidermal Nerve Fiber Density in Rats With Overt Diabetic Polyneuropathy

Saeko Asano, Tatsuhito Himeno, Tomohide Hayami, Mikio Motegi, Rieko Inoue, Hiromi Nakai-Shimoda, Emiri Miura-Yura, Yoshiaki Morishita, Masaki Kondo, Shin Tsunekawa, Yoshiro Kato, Koichi Kato, Keiko Naruse, etc.

J Diabetes Res. 2019 Nov 18;2019:2756020.

PMID: 31828158

1

Safety and Efficacy of Ranirestat in Patients With Mild-To-Moderate Diabetic Sensorimotor Polyneuropathy

Michael Polydefkis, Joseph Arezzo, Marshall Nash, Vera Bril, Aziz Shaibani, Robert J Gordon, Kate L Bradshaw, Roderick W J Junor, Ranirestat Study Group

J Peripher Nerv Syst. 2015 Dec;20(4):363-71.

PMID: 26313450

1

Updates on Aldose Reductase Inhibitors for Management of Diabetic Complications and Non-diabetic Diseases

Ajmer Singh Grewal, Shashikant Bhardwaj, Deepti Pandita, Viney Lather, Bhupinder Singh Sekhon

Mini Rev Med Chem. 2016;16(2):120-62.

PMID: 26349493

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