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RBC8

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For Research Use Only | Not For Clinical Use
CATAP361185424
CAS361185-42-4
MDL NumberMFCD03341241
Molecular Weight424.45
InChI KeyCLMQBVUFKIKYLU-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

Characterisation of the Ral GTPase Inhibitor RBC8 in Human and Mouse Platelets

Tony G Walsh, Andreas Wersäll, Alastair W Poole

Cell Signal. 2019 Jul;59:34-40.

PMID: 30880223

1

Discovery and Characterization of Small Molecules That Target the GTPase Ral

Chao Yan, Degang Liu, Liwei Li, Michael F Wempe, Sunny Guin, May Khanna, Jeremy Meier, Brenton Hoffman, Charles Owens, Christina L Wysoczynski, Matthew D Nitz, William E Knabe, Mansoor Ahmed, David L Brautigan, etc.

Nature. 2014 Nov 20;515(7527):443-7.

PMID: 25219851

1

RalA, a GTPase Targeted by miR-181a, Promotes Transformation and Progression by Activating the Ras-related Signaling Pathway in Chronic Myelogenous Leukemia

Chunming Gu, Maoxiao Feng, Zhao Yin, Xiaochuang Luo, Juhua Yang, Yumin Li, Tianfu Li, Ruirui Wang, Jia Fei

Oncotarget. 2016 Apr 12;7(15):20561-73.

PMID: 26967392

1

RCC2 Interacts With Small GTPase RalA and Regulates Cell Proliferation and Motility in Gastric Cancer

Pengpeng Wang, Wang Zhang, Lili Wang, Wenquan Liang, Aizhen Cai, Yunhe Gao, Lin Chen

Onco Targets Ther. 2020 Apr 14;13:3093-3103.

PMID: 32341655

1

Two-Step Forward Genetic Screen in Mice Identifies Ral GTPase-Activating Proteins as Suppressors of Hepatocellular Carcinoma

Takahiro Kodama, Emilie A Bard-Chapeau, Justin Y Newberg, Michiko Kodama, Roberto Rangel, Kosuke Yoshihara, Jerrold M Ward, Nancy A Jenkins, Neal G Copeland

Gastroenterology. 2016 Aug;151(2):324-337.e12.

PMID: 27178121

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