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Retro-2

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For Research Use Only | Not For Clinical Use
CATIAR42415426
Molecular Weight320.41
DescriptionA cell-permeable tricyclic imine compound that inhibits the endosome-to-Golgi retrograde transport, but not cellular uptake, of CtxB, StxB without affecting cellular uptake/trafficking of Tf or EGF.
SolubilityDMSO: 50 mg/mL
Assay≥95% (HPLC)
Colortan
Formpowder; protect from light
Size25MG
Storage Conditions+2C to +8C
1

Antiviral Effect of Retro-2.1 Against Herpes Simplex Virus Type 2 In Vitro

Wen Dai, Yu Wu, Jin Bi, Jing Wang, Shuai Wang, Wei Kong, Julien Barbier, Jean-Christophe Cintrat, Feng Gao, Zheng Jiang, Daniel Gillet, Wei Su, Chun Jiang

J Microbiol Biotechnol. 2018 Jun 28;28(6):849-859.

PMID: 29847864

1

Antiviral Effects of Retro-2

Wenwen Dai, Yu Wu, Jinpeng Bi, Xiaotong Lu, Ali Hou, Yan Zhou, Bo Sun, Wei Kong, Julien Barbier, Jean-Christophe Cintrat, Feng Gao, Daniel Gillet, Weiheng Su, Chunlai Jiang

Antiviral Res. 2017 Aug;144:311-321.

PMID: 28688753

1

Chemical Structure of Retro-2, a Compound That Protects Cells Against Ribosome-Inactivating Proteins

Jewn Giew Park, Jennifer Nielsen Kahn, Nilgun E Tumer, Yuan-Ping Pang

Sci Rep. 2012;2:631.

PMID: 22953052

1

Retro-2 and Its Dihydroquinazolinone Derivatives Inhibit Filovirus Infection

Olena Shtanko, Yasuteru Sakurai, Ann N Reyes, Romain Noël, Jean-Christophe Cintrat, Daniel Gillet, Julien Barbier, Robert A Davey

Antiviral Res. 2018 Jan;149:154-163.

PMID: 29175127

1

Retro-2 Protects Cells From Ricin Toxicity by Inhibiting ASNA1-mediated ER Targeting and Insertion of Tail-Anchored Proteins

David W Morgens, Charlene Chan, Andrew J Kane, Nicholas R Weir, Amy Li, Michael M Dubreuil, C Kimberly Tsui, Gaelen T Hess, Adam Lavertu, Kyuho Han, Nicole Polyakov, Jing Zhou, Emma L Handy, Philip Alabi, etc.

Elife. 2019 Nov 1;8:e48434.

PMID: 31674906

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